Evidence map›Paper›PMID 38766112›Full record

ArticlebioRxiv : the preprint server for biology2024

Scheduled feeding improves sleep in a mouse model of Huntington's disease.

Emily Chiem, Kevin Zhao, Derek Dell'Angelica, Cristina A Ghiani, Ketema N Paul, Christopher S Colwell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Emily ChiemDepartment of Integrative Biology and Physiology, University of California Los Angeles.
Kevin ZhaoDepartment of Integrative Biology and Physiology, University of California Los Angeles.
Derek Dell'AngelicaDepartment of Psychiatry & Biobehavioral Sciences, University of California Los Angeles.
Cristina A GhianiDepartment of Pathology and Laboratory Medicine, University of California Los Angeles.ORCID 0000-0002-9867-6185
Ketema N PaulDepartment of Integrative Biology and Physiology, University of California Los Angeles.ORCID 0000-0003-0226-9559
Christopher S ColwellDepartment of Psychiatry & Biobehavioral Sciences, University of California Los Angeles.ORCID 0000-0002-1059-184X

Funding

Time restricted feeding rescues circadian and motor dysfunction in a mouse model of Huntington's diseaseR21NS115041 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLWELL, CHRISTOPHER SCOTT, PAUL, KETEMA N · 2020 to 2021
$547k
NINDS NIH HHS R21 NS115041
6 · The paper itself

Abstract

Sleep disturbances are common features of neurodegenerative disorders including Huntington's disease (HD). The sleep and circadian disruptions are recapitulated in animal models, and these models provide the opportunity to evaluate whether circadian interventions can be effective countermeasures for neurodegenerative disease. Time restricted feeding (TRF) interventions successfully improve activity rhythms, sleep behavior and motor performance in mouse models of HD. Seeking to determine if these benefits of scheduled feeding extend to physiological measures of sleep, electroencephalography (EEG) was used to measure sleep/wake states and polysomnographic patterns in adult mice (six mo-old) under TRF and

Indexed as

BACHDEEGHuntington’s diseasesexsleeptime restricted feeding

Identifiers

PMID38766112
PMCPMC11100594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.