Evidence map›Paper›PMID 38766089›Full record

ArticlebioRxiv : the preprint server for biology2024

scDAPP: a comprehensive single-cell transcriptomics analysis pipeline optimized for cross-group comparison.

Alexander Ferrena, Xiang Yu Zheng, Kevyn Jackson, Bang Hoang, Bernice Morrow, Deyou Zheng

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alexander FerrenaDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Xiang Yu ZhengDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Kevyn JacksonDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Bang HoangDepartment of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Bernice MorrowDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Deyou ZhengDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0003-4354-5337

Funding

Cell fate choices by Tbx1 in forming the mammalian heartR01HL153920 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BERNICE E MORROW, Deyou Zheng · 2020 to 2026
$4.0M
Genetic modifiers of congenital heart disease in 22q11.2 deletion syndromeR01HL157157 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI MORROW, BERNICE E · 2022 to 2025
$3.1M
Molecular pathogenesis of congenital heart disease mediated by neural crest and second heart field cellsR01HL163667 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI MORROW, BERNICE E, ZHENG, DEYOU · 2022 to 2025
$2.5M
Leveraging Tumor Suppressor Inactivation for Osteosarcoma TherapyR01CA255643 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HOANG, BANG H · 2021 to 2024
$1.7M
NCI NIH HHS R01 CA255643NHLBI NIH HHS R01 HL153920NHLBI NIH HHS R01 HL157157NHLBI NIH HHS R01 HL163667
6 · The paper itself

Abstract

Single-cell transcriptomics profiling has increasingly been used to evaluate cross-group differences in cell population and cell-type gene expression. This often leads to large datasets with complex experimental designs that need advanced comparative analysis. Concurrently, bioinformatics software and analytic approaches also become more diverse and constantly undergo improvement. Thus, there is an increased need for automated and standardized data processing and analysis pipelines, which should be efficient and flexible too. To address these, we develop the

Identifiers

PMID38766089
PMCPMC11100619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.