Evidence map›Paper›PMID 38765985›Full record

ArticlebioRxiv : the preprint server for biology2025

Intradental mechano-nociceptors serve as sentinels that prevent tooth damage.

Elizabeth A Ronan, Akash R Gandhi, Karin H Uchima Koecklin, Yujia Hu, Shuhao Wan, Brian S C Constantinescu, Mak E Guenther, Maximilian Nagel, Ling-Yu Liu, Aditi Jha and 8 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Elizabeth A RonanORCID 0000-0001-7400-5718
Akash R Gandhi
Karin H Uchima Koecklin
Yujia Hu
Shuhao Wan
Brian S C Constantinescu
Mak E Guenther
Maximilian Nagel
Ling-Yu Liu
Aditi Jha
Leen Dakhilalla
Kaitlyn J Blumberg
Isaac T Berthaume
Tomer Stern
Kevin P Pipe
Peng Li

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Determining the functions of tooth-innervating neurons in dental sensationK22DE029779 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EMRICK, JOSHUA JAMES · 2022 to 2024
$742k
NIDCD NIH HHS T32 DC000011NIDCR NIH HHS K22 DE029779NIDCR NIH HHS T32 DE007057
6 · The paper itself

Abstract

Pain is the anticipated output of the trigeminal sensory neurons that innervate the tooth's vital interior

Identifiers

PMID38765985
PMCPMC11100775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.