Evidence map›Paper›PMID 38765761›Full record

ArticleOne health (Amsterdam, Netherlands)2024

Domestic dogs as environmental sentinel in comparative toxicologic pathology: Assessment of metals and rare earth elements concentrations in healthy and neoplastic mammary glands.

Sabrina V P Defourny, Giulia Caioni, Mirella Bellocci, Valeria Melai, Giampiero Scortichini, Romolo Salini, Michele Martino, Giovanni Di Teodoro, Antonio Cocco, Maria Chiara Cantelmi and 2 more

Abstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sabrina V P DefournyIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Giulia CaioniDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Mirella BellocciIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Valeria MelaiIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Giampiero ScortichiniIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Romolo SaliniIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Michele MartinoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Giovanni Di TeodoroIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Antonio CoccoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Maria Chiara CantelmiIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.
Carmine MerolaDepartment of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Antonio PetriniIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantification of trace element concentrations in human and animal tissues has acquired great importance in the last few years, considering the pivotal role of these elements in several physiological and pathological processes. Variations in their concentrations appear to have a role in the development and advancement of diseases in both humans and animals, for example, cancer. The purpose of this study was to investigate the concentration of rare earth elements and metals in healthy and neoplastic Formalin-Fixed Paraffin-Embedded (FFPE) mammary gland tissue of dogs. All samples were processed to have a quantitative determination of inorganic elements including metals of known toxicological interest such as Pb, Cd, Tl, As, Hg, the trace elements Mn, Fe, Co, Cu, Zn, Se, and other elements including Cr, V, Mo, Ni, Sb, W, Sn. Moreover, rare earth elements (REEs) (Sc, Y, Lu, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb) were also investigated. Cu and Mo concentrations in mammary cancerous tissue were greater than those in normal mammary glands (

Indexed as

cancerDomestic animalsInorganic elementsRare earthSentinelToxicologic pathology

Identifiers

PMID38765761
PMCPMC11101696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.