Evidence map›Paper›PMID 38765731›Full record

ArticlePediatric diabetes2023

DNA Methylation Near

Randi K Johnson, Amanda J Ireton, Patrick M Carry, Lauren A Vanderlinden, Fran Dong, Alex Romero, David R Johnson, Debashis Ghosh, Fan Yang, Brigitte Frohnert and 4 more

Abstract read
In one paragraph

Article in Pediatric diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Randi K JohnsonDepartment of Biomedical Informatics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-9345-4439
Amanda J IretonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Patrick M CarryDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-2989-7080
Lauren A VanderlindenDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-4019-8395
Fran DongBarbara Davis Center for Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Alex RomeroDepartment of Biomedical Informatics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
David R JohnsonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Debashis GhoshDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-6618-1316
Fan YangDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Brigitte FrohnertBarbara Davis Center for Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Ivana V YangDepartment of Biomedical Informatics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-1018-489X
Katerina KechrisDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-3725-5459
Marian RewersBarbara Davis Center for Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jill M NorrisDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-8674-2598

Funding

Natural History of Pre-Diabetic Autoimmunity (DAISY)R01DK032493 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 1986 to 2024
$9.3M
Nutrigenetics & -genomics of Vitamin D and Omega-3 Fatty Acids in Type 1 DiabetesR01DK104351 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI NORRIS, JILL M · 2014 to 2018
$2.9M
Islet Autoimmunity Reversion as a Model of T1D ResiliencyR21AI142483 · NIAID · UNIVERSITY OF COLORADO DENVER · PI NORRIS, JILL M · 2019 to 2020
$428k
NIAID NIH HHS R21 AI142483NIDDK NIH HHS R01 DK032493NIDDK NIH HHS R01 DK104351
6 · The paper itself

Abstract

Given the differential risk of type 1 diabetes (T1D) in offspring of affected fathers versus affected mothers and our observation that T1D cases have differential DNA methylation near the imprinted

Indexed as

Diabetes Mellitus, Type 1DNA MethylationGenetic Predisposition to DiseaseAdolescentCase-Control StudiesChildChild, PreschoolCpG IslandsFemaleGTPase-Activating ProteinsHumansMaleNerve Tissue ProteinsRisk FactorsDLGAP2 protein, humanGTPase-Activating ProteinsNerve Tissue Proteins

Identifiers

PMID38765731
PMCPMC11100224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.