Evidence map›Paper›PMID 38765505›Full record

Trial reportRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2024

Impact of doula's continuous support on serotonin release in parturients: a pilot randomized clinical trial.

Eleonora de Deus Vieira de Moraes, Mayara Segundo Ribeiro, Cíntia Erbert, Caio Antonio de Campos Prado, Elaine Christine Dantas Moisés

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eleonora de Deus Vieira de MoraesUniversidade de São Paulo Ribeirão Preto Medical School São PauloSP Brazil Ribeirão Preto Medical School, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-3716-1938
Mayara Segundo RibeiroUniversidade de São Paulo Ribeirão Preto Medical School São PauloSP Brazil Ribeirão Preto Medical School, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-5811-2732
Cíntia ErbertWomen's Health Reference Center of Ribeirão Preto São Paulost Brazil Women's Health Reference Center of Ribeirão Preto, São Paulo, st, Brazil.ORCID https://orcid.org/0000-0002-4016-0485
Caio Antonio de Campos PradoWomen's Health Reference Center of Ribeirão Preto São Paulost Brazil Women's Health Reference Center of Ribeirão Preto, São Paulo, st, Brazil.ORCID https://orcid.org/0000-0003-1767-4725
Elaine Christine Dantas MoisésUniversidade de São Paulo Ribeirão Preto Medical School São PauloSP Brazil Ribeirão Preto Medical School, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-9099-4544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate whether the continuous support provided by doulas influences the endogenous release of serotonin in parturients. Methods: This pilot study included 24 primigravidae at term. Of these, 12 women received continuous doula support (Experimental Group), whereas the other 12 received the usual assistance without doula support (Control Group). Blood samples were collected from all the women at the active and expulsion stages of labor and at the fourth period of labor (Greenberg period) for evaluation of their serotonin levels using high-performance liquid chromatography. Results: The average serotonin concentrations in the control and experimental groups were respectively 159.33 and 150.02 ng/mL at the active stage, 179.13 and 162.65 ng/mL at the expulsion stage, and 198.94 and 221.21 ng/mL at the Greenberg period. There were no statistically significant differences in serotonin concentrations between the two groups at the active and expulsion stages of labor. By contrast, within the experimental group, a significant increase in serotonin concentration was observed in the Greenberg period compared with the levels in the active and expulsion stages (p < 0.05). Conclusion: The novelty of this study relies on the ability to correlate the influence of the continuous support offered by doulas with the release of serotonin in parturients, with the results suggesting that the assistance received during labor can modulate the levels of hormone release in the Greenberg period. Brazilian Registry of Clinical Trials: RBR-4zjjm4h.

Indexed as

SerotoninAdultDoulasFemaleHumansLabor, ObstetricPilot ProjectsPregnancyYoung AdultSerotoninDoulasHumanized deliveryLaborPregnant womenSerotonin

Identifiers

PMID38765505
PMCPMC11075389

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.