Evidence map›Paper›PMID 38765017›Full record

ReviewFrontiers in immunology2024

Emerging role of gut microbiota in autoimmune diseases.

Xinyi Wang, Wei Yuan, Chunjuan Yang, Zhangxue Wang, Jin Zhang, Donghua Xu, Xicai Sun, Wenchang Sun

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyi WangSchool of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Wei YuanDepartment of Radiation Oncology, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Chunjuan YangDepartment of Central Laboratory, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Zhangxue WangDepartment of Rheumatology, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Jin ZhangDepartment of Rheumatology, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Donghua XuDepartment of Central Laboratory, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Xicai SunDepartment of Hospital Office, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Wenchang SunDepartment of Central Laboratory, The First Affiliated Hospital of Shandong Second Medical University, Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating studies have indicated that the gut microbiota plays a pivotal role in the onset of autoimmune diseases by engaging in complex interactions with the host. This review aims to provide a comprehensive overview of the existing literatures concerning the relationship between the gut microbiota and autoimmune diseases, shedding light on the complex interplay between the gut microbiota, the host and the immune system. Furthermore, we aim to summarize the impacts and potential mechanisms that underlie the interactions between the gut microbiota and the host in autoimmune diseases, primarily focusing on systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, type 1 diabetes mellitus, ulcerative colitis and psoriasis. The present review will emphasize the clinical significance and potential applications of interventions based on the gut microbiota as innovative adjunctive therapies for autoimmune diseases.

Indexed as

Autoimmune DiseasesGastrointestinal MicrobiomeAnimalsAutoimmunityDysbiosisHumansautoimmune diseasegut microbiotahomeostasismicrobiomeprobiotics

Identifiers

PMID38765017
PMCPMC11099291

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.