ArticlePsychiatry and clinical psychopharmacology2022
Differential Diagnosis Findings Between Alzheimer's Disease and Major Depressive Disorder: A Review.
Article in Psychiatry and clinical psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Uncovering the genetic underpinnings for different psychiatric disorder combinations.Psychological medicine · 2025Article
- Quality of Life in the Face of Depression Among Older People: A Cross-Sectional Study in Brazil and Portugal.Psychiatry and clinical psychopharmacology · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Differentiating diagnosis between Alzheimer's disease and major depressive disorder in the elderly is a great clinical challenge. This study aimed to identify the establishment of differential diagnosis protocols between Alzheimer's disease and major depressive disorder. Methods: We searched studies in the Ovid MEDLINE, EMBASE, PsycINFO, and Web of Science databases between 2009 and 2019. A total of 155 references were found for searching relevant articles using Boolean search. After exclusion of redundancies and assessing of title, abstract, and full text for eligibility, 11 articles were selected. The total sample size was 1077 distributed in 8 different countries. Results: Significant results were found for differential diagnosis between Alzheimer's disease and major depressive disorder, such as overall mental status, episodic memory, visuospatial construction, delayed recognition task, semantic verbal fluency, visual task in short-term memory, atrophy of the hippocampus, cortical activation in specific tasks, and cerebrospinal fluid biomarkers. Conclusion: These findings are good pathways for discriminating Alzheimer's disease from major depression in the elderly.
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