Evidence map›Paper›PMID 38764824›Full record

ArticleWorld journal of gastrointestinal oncology2024

Chemoradiotherapy plus tislelizumab for mismatch repair proficient rectal cancer with supraclavicular lymph node metastasis: A case report.

Wen-Tao Zhong, Yuan Lv, Qian-Yu Wang, Ran An, Gang Chen, Jun-Feng Du

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Tao ZhongThe Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Yuan LvDepartment of General Surgery, The 7 Medical Center of PLA General Hospital, Beijing 100700, China.
Qian-Yu WangDepartment of General Surgery, The 7 Medical Center of PLA General Hospital, Beijing 100700, China.
Ran AnDepartment of Pathology, The 7 Medical Center of PLA General Hospital, Beijing 100700, China.
Gang ChenDepartment of General Surgery, The 7 Medical Center of PLA General Hospital, Beijing 100700, China.
Jun-Feng DuDepartment of General Surgery, The 7 Medical Center of PLA General Hospital, Beijing 100700, China. dujunfeng@301hospital.com.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to the latest report, colorectal cancer is still one of the most prevalent cancers, with the third highest incidence and mortality worldwide. Treatment of advanced rectal cancer with distant metastases is usually unsatisfactory, especially for mismatch repair proficient (pMMR) rectal cancer, which leads to poor prognosis and recurrence. CASE SUMMARY: We report a case of a pMMR rectal adenocarcinoma with metastases of multiple lymph nodes, including the left supraclavicular lymph node, before treatment in a 70-year-old man. He received full courses of chemoradiotherapy (CRT) followed by 4 cycles of programmed death 1 inhibitor Tislelizumab, and a pathologic complete response (pCR) was achieved, and the lesion of the left supraclavicular lymph node also disappeared.

conclusionpMMR advanced rectal cancer with preserved intact distant metastatic lymph nodes may benefit from full-course CRT combined with immunotherapy.

Indexed as

Case reportChemoradiotherapyImmunotherapyMetastasisPrognosisRectal cancer

Identifiers

PMID38764824
PMCPMC11099463

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