Evidence map›Paper›PMID 38764771›Full record

ReviewWorld journal of gastroenterology2024

Selective internal radiation therapy segmentectomy: A new minimally invasive curative option for primary liver malignancies?

Riccardo Inchingolo, Francesco Cortese, Antonio Rosario Pisani, Fabrizio Acquafredda, Roberto Calbi, Riccardo Memeo, Fotis Anagnostopoulos, Stavros Spiliopoulos

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Riccardo InchingoloUnit of Interventional Radiology, "F. Miulli" Regional General Hospital, Bari 70021, Italy. riccardoin@hotmail.it.
Francesco CorteseUnit of Interventional Radiology, "F. Miulli" Regional General Hospital, Bari 70021, Italy.
Antonio Rosario PisaniInterdisciplinary Department of Medicine, Section of Nuclear Medicine, University of Bari "Aldo Moro", Bari 70121, Italy.
Fabrizio AcquafreddaUnit of Interventional Radiology, "F. Miulli" Regional General Hospital, Bari 70021, Italy.
Roberto CalbiDepartment of Radiology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti 70021, Italy.
Riccardo MemeoUnit of Hepato-Pancreatic-Biliary Surgery, "F. Miulli" Regional General Hospital, Bari 70021, Italy.
Fotis AnagnostopoulosThe Second Radiology Department, National and Kapodistrian University of Athens, Chaidari Athens 12461, Greece.
Stavros SpiliopoulosThe Second Radiology Department, National and Kapodistrian University of Athens, Chaidari Athens 12461, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transarterial radioembolization or selective internal radiation therapy (SIRT) has emerged as a minimally invasive approach for the treatment of tumors. This percutaneous technique involves the local, intra-arterial delivery of radioactive microspheres directly into the tumor. Historically employed as a palliative measure for liver malignancies, SIRT has gained traction over the past decade as a potential curative option, mirroring the increasing role of radiation segmentectomy. The latest update of the BCLC hepatocellular carcinoma guidelines recognizes SIRT as an effective treatment modality comparable to other local ablative methods, particularly well-suited for patients where surgical resection or ablation is not feasible. Radiation segmentectomy is a more selective approach, aiming to deliver high-dose radiation to one to three specific hepatic segments, while minimizing damage to surrounding healthy tissue. Future research efforts in radiation segmentectomy should prioritize optimizing radiation dosimetry and refining the technique for super-selective administration of radiospheres within the designated hepatic segments.

Indexed as

Carcinoma, HepatocellularHepatectomyLiver NeoplasmsBrachytherapyEmbolization, TherapeuticHumansLiverMicrospheresPractice Guidelines as TopicTreatment OutcomeYttrium RadioisotopesYttrium RadioisotopesHepatocellular carcinomaPersonalised dosimetryPrimary liver malignanciesRadiation segmentectomySelective internal radiation therapyTransarterial radioembolization

Identifiers

PMID38764771
PMCPMC11099395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.