Evidence map›Paper›PMID 38764580›Full record

ArticleFrontiers in oncology2024

Case report: 'Atypical Richter transformation from CLL-type monoclonal B-cell lymphocytosis into Burkitt lymphoma in a treatment naïve patient'.

Annaïse J Jauch, Ilaria Alborelli, Andreas Reusser, Albert Baschong, Cyrill Rütsche, Olivier Bignucolo, Jakob Passweg, Stefan Dirnhofer, Fatime Krasniqi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A Literature Review About Richter's Syndrome Presented in the Mouth.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Annaïse J JauchDivision of Medical Oncology, University Hospital of Basel, Basel, Switzerland.
Ilaria AlborelliInstitute of Medical Genetics & Pathology, Pathology, University Hospital Basel, Basel, Switzerland.
Andreas ReusserDivision of Medical Oncology, Kantonsspital Basel-Land, Liestal, Switzerland.
Albert BaschongInstitute for Pathology, Kantonsspital Basel-Land, Liestal, Switzerland.
Cyrill RütscheDivision of Hematology, University Hospital Basel, Basel, Switzerland.
Olivier BignucoloSwiss Institute of Bioinformatics (SIB), Department of Biomedical Sciences, University of Lausanne, Basel, Switzerland.
Jakob PasswegDivision of Hematology, University Hospital Basel, Basel, Switzerland.
Stefan DirnhoferInstitute of Medical Genetics & Pathology, Pathology, University Hospital Basel, Basel, Switzerland.
Fatime KrasniqiDivision of Medical Oncology, University Hospital of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Richter transformation refers to the progression of an initially slow-growing small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) into an aggressive lymphoma, typically diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma. Case presentation: The patient presented with a rapid onset of localized cervical swelling, accompanied by monoclonal B-cell lymphocytosis displaying a CLL immunophenotype. The histopathological analysis identified a Burkitt lymphoma (BL) located in the submandibular gland and adjacent lymph node. The patient's bone marrow displayed a minor infiltration of monoclonal B-cells with a CLL immunophenotype (< 10%). Molecular analysis demonstrated the presence of the same monoclonal rearrangement in the framework region (FR3 region) of the immunoglobulin heavy chain ( Conclusion: This report provides an exceptionally rare description of a CLL-type monoclonal B-cell lymphocytosis transforming into a very aggressive Burkitt lymphoma in a treatment naïve patient.

Indexed as

Burkitt lymphomaMBLRichter transformationSLL/CLLstate sequencing

Identifiers

PMID38764580
PMCPMC11099200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.