Evidence map›Paper›PMID 38764228›Full record

ArticleAsian spine journal2024

Prognostic Factors after Surgical Treatment for Spinal Metastases.

Kazuhiro Murotani, Shunsuke Fujibayashi, Bungo Otsuki, Takayoshi Shimizu, Takashi Sono, Eijiro Onishi, Hiroaki Kimura, Yasuyuki Tamaki, Naoya Tsubouchi, Masato Ota and 3 more

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Article in Asian spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kazuhiro MurotaniDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shunsuke FujibayashiDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Bungo OtsukiDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takayoshi ShimizuDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takashi SonoDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Eijiro OnishiDepartment of Orthopaedic Surgery, Kobe City Medical Center General Hospital, Hyogo, Japan.
Hiroaki KimuraDepartment of Orthopaedic Surgery, Amagasaki General Medical Center, Hyogo, Japan.
Yasuyuki TamakiDepartment of Orthopaedic Surgery, Wakayama Red Cross Hospital, Wakayama, Japan.
Naoya TsubouchiDepartment of Orthopaedic Surgery, Kyoto Medical Center, Kyoto, Japan.
Masato OtaDepartment of Orthopaedic Surgery, Kitano Hospital, Osaka, Japan.
Ryosuke TsutsumiDepartment of Orthopaedic Surgery, Osaka Red-Cross Hospital, Osaka, Japan.
Tatsuya IshibeShiga Spine Center, Hino Memorial Hospital, Shiga, Japan.
Shuichi MatsudaDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA retrospective multicenter case series was conducted. PURPOSE: This study aimed to investigate survival and prognostic factors after surgery for a metastatic spinal tumor. OVERVIEW OF LITERATURE: Prognostic factors after spinal metastasis surgery remain controversial.

methodsA retrospective multicenter study was conducted. The study participants included 345 patients who underwent surgery for spinal metastases from 2010 to 2020 at nine referral spine centers in Japan. Data for each patient were extracted from medical records. To identify the factors predicting survival prognosis after surgery, univariate analyses were performed using a Cox proportional hazards model.

resultsThe mean age was 65.9 years. Common primary tumors were lung (n=72), prostate (n=61), and breast (n=39), and 67.8% (n=234) presented with osteolytic lesions. The epidural spinal cord compression scale score 2 or 3 was recognized in 79.0% (n=271). Frankel grade A paralysis accounted for 1.4% (n=5), and 73.3% (n=253) were categorized as intermediate or high risk according to the new Katagiri score. The overall survival rates were -71.0% at 6 months, 57.4% at 12, and 43.3% at 24. In the univariate analysis, Frankel grade A (hazard ratio [HR], 3.59; 95% confidence interval [CI], 1.23-10.50; p<0.05), intermediate risk (HR, 3.34; 95% CI, 2.10-5.32; p<0.01), and high risk (HR, 7.77; 95% CI, 4.72-12.8; p<0.01) in the new Katagiri score were significantly associated with poor survival. On the contrary, postoperative chemotherapy (HR, 0.23; 95% CI, 0.15-0.36; p<0.01), radiation therapy (HR, 0.43; 95% CI, 0.26-0.70; p<0.01), and both adjuvant therapy (HR, 0.21; 95% CI, 0.14-0.32; p<0.01) were suggested to improve survival.

conclusionsSurgical indications for patients with Frankel grade A or intermediate or high risk in the new Katagiri score should be carefully considered because of poor survival. Chemotherapy or radiation therapy should be considered after surgery for better survival.

Indexed as

EpidemiologyKatagiri scoreNeoplasm metastasisPrognosisSpine surgery

Identifiers

PMID38764228
PMCPMC11222892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.