Evidence map›Paper›PMID 38762845›Full record

ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2024

Left ventricular function assessment in Kawasaki disease by two-dimensional global longitudinal systolic strain with automated function imaging.

Ehsan Aghaei Moghadam, Maryam Taraz, Aliakbar Zeinaloo, Mohammad Taghi Majnoon, Keyhan Sayadpour Zanjani, Mojtaba Gorgi

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Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ehsan Aghaei MoghadamCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran.
Maryam TarazCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran.
Aliakbar ZeinalooCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran.
Mohammad Taghi MajnoonCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran.
Keyhan Sayadpour ZanjaniCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran. ksayadpour@gmail.com.ORCID http://orcid.org/0000-0002-4640-4399
Mojtaba GorgiCardiology Division, Pediatric Department, Children's Medical Center (Pediatric Center of Excellence), Tehran University of Medical Sciences, No. 346, Keshavarz Blvd, Tehran, 14188, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKawasaki disease is an acute febrile vasculitis of childhood mainly affecting children under 4 years of age. In the acute stage of the disease, heart function decreases and gradually returns to normal after treatment. However, subendocardial involvement may persist, which cannot be assessed by M-mode echocardiography. Strain echocardiography is a recently developed technique to assess subendocardial involvement of myocardial deformation. We aimed to study the stratified strain of left ventricular function in a Kawasaki patient at least 6 months after the acute stage of the disease with special conditions for entering the study using two-dimensional speckle-tracking imaging. Between September 2020 and October 2022, 27 healthy children and 27 children with a history of Kawasaki disease more than 6 months ago were evaluated using two-dimensional global longitudinal peak systolic strain with automated function imaging technology.

resultsThe mean age of patients was 5.6 years. With M-mode echocardiography, ejection fraction of each group was in the normal range. Mean (± standard deviation) global longitudinal peak strain in four-chamber view of girls with Kawasaki disease was - 23.74 ± 2.77, and that in boys with Kawasaki disease was - 20.93 ± 2.06 (P value = 0.008). GLPS (global longitudinal peak strain) was compared as an overall average and as in a separate segment, which showed significant difference in two comparisons. In our study, a decrease in the function of some cardiac segments is reported. Global longitudinal peak strain in four-chamber view was significantly lower in boys. Comparing different segments, a difference in global left ventricular long-axis strain was found between the two groups. On the other hand, there was a major difference between the two groups in the basal inferolateral, basal anterolateral, and mid-inferolateral, which receives blood from Left Circumflex artery.

conclusionUsing stain echocardiography to detect continued subendocardial involvement in asymptomatic children with a history of Kawasaki disease for a better understanding of the condition, effective management and follow-up is recommended.

Indexed as

Automated function imagingCardiac involvementChildrenKawasaki disease

Identifiers

PMID38762845
PMCPMC11102889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.