Evidence map›Paper›PMID 38762698›Full record

ArticleActa neurologica Belgica2024

Neuropathological evidence for neurosarcoidosis is more widespread than imaging suggests.

D P Kidd, F Jabeen, M Galloway

Abstract readCase Reports
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In one paragraph

Article in Acta neurologica Belgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D P KiddEmeritus, The Centre for Neurosarcoidosis, Neuroimmunology Unit, Institute of Immunity and Transplantation clinic, Royal Free Hospital, Hampstead, London, NW3 2QG, UK. desmond.kidd@nhs.net.ORCID http://orcid.org/0000-0002-2415-9011
F JabeenDepartment of Neuroradiology, Royal Free Hospital, Hampstead, London, NW3 2QG, UK.
M GallowayEmeritus, Department of Cellular Pathology, Royal Free Hospital, Hampstead, London, NW3 2QG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a single case of a 47 year old male with a relapsing progressive neurological disease characterised by an infiltrative inflammation of the brain and leptomeninges. Investigations revealed the presence of systemic sarcoidosis which was confirmed histologically following a mediastinal lymph node biopsy. The imaging appearances of the brain and spinal canal lesions were compatible with neurological involvement by the same disease. Despite treatment, the patient deteriorated and died. We present the neuropathological findings, correlate these with the imaging features, and find that neuropathological evidence for disease was in this case strikingly more widespread than predicted by imaging ante-mortem.

Indexed as

Central Nervous System DiseasesSarcoidosisBrainHumansMagnetic Resonance ImagingMaleMiddle AgedImagingNeuropathologyNeurosarcoidosisSarcoidosisTreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.