Evidence map›Paper›PMID 38762673›Full record

ArticleScientific reports2024

Contrast-enhanced ultrasound for differentiating benign from malignant focal solid renal lesions in pediatric patients.

Yusi Fu, Jia Zhong, Yan Tan, Taiqing Zheng, Minghui Liu, Guotao Wang

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
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4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yusi FuDepartment of Ultrasound Diagnosis, The Second Xiang ya Hospital, Central South University, No 139, Renmin Middle Road, Changsha, 410011, Hunan, People's Republic of China.
Jia ZhongDepartment of Ultrasound, Mawangdui District of Hunan Provincial People's Hospital, Hunan Normal University, No 89, Guhan Road, Changsha, 410000, Hunan, People's Republic of China.
Yan TanDepartment of Ultrasound Diagnosis, The Second Xiang ya Hospital, Central South University, No 139, Renmin Middle Road, Changsha, 410011, Hunan, People's Republic of China.
Taiqing ZhengDepartment of Pathology, Hunan Children's Hospital, No 86, Ziyuan Road, Changsha, 410007, Hunan, People's Republic of China.
Minghui LiuDepartment of Ultrasound Diagnosis, The Second Xiang ya Hospital, Central South University, No 139, Renmin Middle Road, Changsha, 410011, Hunan, People's Republic of China.
Guotao WangDepartment of Ultrasound Diagnosis, The Second Xiang ya Hospital, Central South University, No 139, Renmin Middle Road, Changsha, 410011, Hunan, People's Republic of China. wanggt6@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contrast-enhanced ultrasound (CEUS) has been mainly applied to adults to differentiate benign and malignant renal lesions, however, the characteristics of CEUS in pediatric has not been as well studied as in adults. In the present work, the eligible pediatric patients who underwent renal CEUS between March 2016 and February 2023 were retrospectively analyzed. It included 20 lesions (median diameter, 8.4 cm; range, 1.8-18.0 cm) from 20 patients (median age, 28.0 months; range, 3.0-212.0 months; 9 boys) in malignant group and 5 lesions (median diameter, 3.8 cm; range, 1.3-7.5 cm) from 5 patients (median age, 25.0 months; range, 0.7-216.0 months; 2 boys) in benign group. The diagnostic performance was assessed. Nonparametric and Chi-square tests were performed. With hyperenhancement plus wash-out, CEUS showed a sensitivity of 95.0% [95% confidence interval (CI): 75.1%, 99.9%], a specificity of 80.0% (CI: 28.4%, 99.5%), a positive predictive value of 95.0% (CI: 75.1%, 99.9%) and a negative predictive value of 80.0% (CI: 28.4%, 99.5%). It suggested that CEUS is a valuable technique for identifying between malignant and benign renal lesions in children.

Indexed as

Contrast MediaKidney NeoplasmsUltrasonographyAdolescentChildChild, PreschoolDiagnosis, DifferentialFemaleHumansInfantKidneyMaleRetrospective StudiesSensitivity and SpecificityContrast MediaChildrenContrast-enhanced ultrasoundRenal lesionWilms tumor

Identifiers

PMID38762673
PMCPMC11102535

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