Evidence map›Paper›PMID 38762571›Full record

ArticleScientific reports2024

Antiepileptic drug-loaded and multifunctional iron oxide@silica@gelatin nanoparticles for acid-triggered drug delivery.

Nazanin Ghane, Shahla Khalili, Saied Nouri Khorasani, Oisik Das, Seeram Ramakrishna, Rasoul Esmaeely Neisiany

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nazanin GhaneDepartment of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Shahla KhaliliDepartment of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Saied Nouri KhorasaniDepartment of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran. saied@iut.ac.ir.
Oisik DasDepartment of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 97187, Luleå, Sweden. oisik.das@ltu.se.
Seeram RamakrishnaCenter for Nanotechnology & Sustainability, National University of Singapore, Singapore, 117574, Singapore.
Rasoul Esmaeely NeisianyDepartment of Polymer Engineering, Hakim Sabzevari University, Sabzevar, 9617976487, Iran. r.esmaeely@hsu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study developed an innovative design for the production of smart multifunctional core-double shell superparamagnetic nanoparticles (NPs) with a focus on the development of a pH-responsive drug delivery system tailored for the controlled release of Phenytoin, accompanied by real-time monitoring capabilities. In this regard, the ultra-small superparamagnetic iron oxide@silica NPs (IO@Si MNPs) were synthesized and then coated with a layer of gelatin containing Phenytoin as an antiepileptic drug. The precise saturation magnetization value for the resultant NPs was established at 26 emu g

Indexed as

AnticonvulsantsDrug Delivery SystemsGelatinPhenytoinSilicon DioxideDrug CarriersDrug LiberationFerric CompoundsHumansHydrogen-Ion ConcentrationMagnetic Iron Oxide NanoparticlesMagnetite NanoparticlesNanoparticlesParticle SizeAnticonvulsantsDrug CarriersFerric Compoundsferric oxideGelatinMagnetite NanoparticlesPhenytoinSilicon DioxideAntiepileptic drugDrug deliveryGelatinPhenytoinpH-sensitivitySilicaSuperparamagnetic nanoparticles

Identifiers

PMID38762571
PMCPMC11102556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.