Evidence map›Paper›PMID 38761717›Full record

ArticleChild abuse & neglect2024

Understanding forms of childhood adversities and associations with adult health outcomes: A regression tree analysis.

Sara P Perrins, Ellen Vermes, Kristen Cincotta, Ye Xu, Lucas Godoy-Garraza, May S Chen, Ronnesha Addison, Brooke Douglas, Allison Yatco, Nimi Idaikkadar and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Child abuse & neglect, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara P PerrinsICF, 1902 ICF Reston Plaza, Reston, VA 20190, USA. Electronic address: Sara.Perrins@ICF.com.
Ellen VermesICF, 1902 ICF Reston Plaza, Reston, VA 20190, USA.
Kristen CincottaICF, 1902 ICF Reston Plaza, Reston, VA 20190, USA.
Ye XuICF, 1902 ICF Reston Plaza, Reston, VA 20190, USA.
Lucas Godoy-GarrazaICF, 1902 ICF Reston Plaza, Reston, VA 20190, USA.
May S ChenCenters for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Violence Prevention, 4770 Buford Highway NE, Mailstop S106-10, Atlanta, GA 30341-3717, USA.
Ronnesha AddisonCenters for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Injury Prevention, 4770 Buford Highway NE, Mailstop S106-8, Atlanta, GA 30341-3717, USA.
Brooke DouglasCenters for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Violence Prevention, 4770 Buford Highway NE, Mailstop S106-10, Atlanta, GA 30341-3717, USA.
Allison YatcoOak Ridge Institute for Science and Education, 100 ORAU Way, Oak Ridge, TN 37830, USA.
Nimi IdaikkadarCenters for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Injury Prevention, 4770 Buford Highway NE, Mailstop S106-8, Atlanta, GA 30341-3717, USA.
Leigh A WillisCenters for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Violence Prevention, 4770 Buford Highway NE, Mailstop S106-10, Atlanta, GA 30341-3717, USA.

Funding

Intramural CDC HHS CC999999NCIPC CDC HHS GS00Q14OADU209
6 · The paper itself

Abstract

backgroundEmpirical studies have demonstrated associations between ten original adverse childhood experiences (ACEs) and multiple health outcomes. Identifying expanded ACEs can capture the burden of other childhood adversities that may have important health implications.

objectiveWe sought to identify childhood adversities that warrant consideration as expanded ACEs. We hypothesized that experiencing expanded and original ACEs would be associated with poorer adult health outcomes compared to experiencing original ACEs alone.

participantsThe 11,545 respondents of the National Longitudinal Surveys (NLS) and Child and Young Adult Survey were 48.9 % female, 22.7 % Black, 15.8 % Hispanic, 36.1 % White, 1.7 % Asian/Native Hawaiian/Pacific Islander/Native American/Native Alaskan, and 7.5 % Other.

methodsThis study used regression trees and generalized linear models to identify if/which expanded ACEs interacted with original ACEs in association with six health outcomes.

resultsFour expanded ACEs-basic needs instability, lack of parental love and affection, community stressors, and mother's experience with physical abuse during childhood -significantly interacted with general health, depressive symptom severity, anxiety symptom severity, and violent crime victimization in adulthood (all p-values <0.005). Basic needs instability and/or lack of parental love and affection emerged as correlates across multiple outcomes. Experiencing lack of parental love and affection and original ACEs was associated with greater anxiety symptoms (p = 0.022).

conclusionsThis is the first study to use supervised machine learning to investigate interaction effects among original ACEs and expanded ACEs. Two expanded ACEs emerged as predictors for three adult health outcomes and warrant further consideration in ACEs assessments.

Indexed as

Adverse Childhood ExperiencesAdolescentAdultAdult Survivors of Child AbuseAnxietyChildCrime VictimsDepressionFemaleHealth StatusHumansLongitudinal StudiesMaleRegression AnalysisUnited StatesYoung AdultACEsBasic needs instabilityChildhood adversityParental carePublic healthRegression tree

Identifiers

PMID38761717
PMCPMC11492381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.