Evidence map›Paper›PMID 38761558›Full record

Trial reportBehaviour research and therapy2024

Neurocognitive functioning in adults with trichotillomania: Predictors of treatment response and symptom severity in a randomized control trial.

Kathryn E Barber, Douglas W Woods, Thilo Deckersbach, Christopher C Bauer, Scott N Compton, Michael P Twohig, Emily J Ricketts, Jordan Robinson, Stephen M Saunders, Martin E Franklin

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathryn E BarberDepartment of Psychology, Marquette University, 317 604 N. 16th St. Milwaukee, WI, 53233, USA. Electronic address: kathryn.barber@marquette.edu.
Douglas W WoodsDepartment of Psychology, Marquette University, 317 604 N. 16th St. Milwaukee, WI, 53233, USA.
Thilo DeckersbachUniversity of Applied Sciences, DIPLOMA Hochschule, Am Hegeberg 2, 37242 Bad Sooden-Allendorf, Germany.
Christopher C BauerMedical College of Wisconsin, Health Resource Center, 8701 Watertown Plank Rd., 5th Floor, Milwaukee, WI, 53226, USA.
Scott N ComptonDepartment of Psychiatry and Behavioral Sciences, Duke University, Duke Child and Family Study Center, 2608 Erwin Road Durham, NC, 27705, USA.
Michael P TwohigUtah State University, Department of Psychology, 2810 Old Main Hill, Logan, UT, 84322, USA.
Emily J RickettsDepartment of Neuroscience, UCLA Semel Institute, 1506 Gonda Center Los Angeles, California, 90095, USA.
Jordan RobinsonJSR Neuropsychological Services, 3209 W 76th St, Edina, MN, 55435, USA.
Stephen M SaundersDepartment of Psychology, Marquette University, 317 604 N. 16th St. Milwaukee, WI, 53233, USA.
Martin E FranklinRogers Behavioral Health, 1 Winding Drive, Suite 106, Philadelphia, PA, 19131, USA.

Funding

Acceptance Enhanced Behavior Therapy for TrichotillomaniaR01MH080966 · NIMH · UNIVERSITY OF WISCONSIN MILWAUKEE · PI WOODS, DOUGLAS W · 2009 to 2013
$1.8M
NIMH NIH HHS R01 MH080966
6 · The paper itself

Abstract

Trichotillomania (TTM) is associated with impairments in response inhibition and cognitive flexibility, but it is unclear how such impairments relate to treatment outcome. The present study examined pre-treatment response inhibition and cognitive flexibility as predictors of treatment outcome, change in these domains from pre-to post-treatment, and associations with TTM severity. Participants were drawn from a randomized controlled trial comparing acceptance-enhanced behavior therapy (AEBT) to psychoeducation and supportive therapy (PST) for TTM. Adults completed assessments at pre-treatment (n = 88) and following 12 weeks of treatment (n = 68). Response inhibition and cognitive flexibility were assessed using the Stop Signal Task and Object Alternation Task, respectively. Participants completed the MGH-Hairpulling Scale. Independent evaluators administered the NIMH-Trichotillomania Severity Scale and Clinical Global Impressions-Improvement Scale. Higher pre-treatment TTM severity was associated with poorer pre-treatment cognitive flexibility, but not response inhibition. Better pre-treatment response inhibition performance predicted positive treatment response and lower post-treatment TTM symptom severity, irrespective of treatment assignment. Cognitive flexibility did not predict treatment response. After controlling for age, neither neurocognitive variable changed during treatment. Response inhibition and cognitive flexibility appear uniquely related to hair pulling severity and treatment response in adults with TTM. Implications for treatment delivery and development are discussed.

Indexed as

Severity of Illness IndexTrichotillomaniaAcceptance and Commitment TherapyAdolescentAdultCognitionExecutive FunctionFemaleHumansInhibition, PsychologicalMaleMiddle AgedTreatment OutcomeYoung AdultCognitive flexibilityInhibitory controlNeurocognitionNeuropsychologyResponse inhibitionTrichotillomania

Identifiers

PMID38761558
PMCPMC11198925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.