Evidence map›Paper›PMID 38761297›Full record

ReviewCurrent pain and headache reports2024

Emerging Medications and Strategies in Acute Pain Management: Evolving Role of Novel Sodium and Calcium Channel Blockers, Peptide-Based Pharmacologic Drugs, and Non-Medicinal Methods.

Alan D Kaye, Driskell R Greene, Catherine Nguyen, Amanda Ragland, Mason P Granger, William Peyton Wilhite, Kylie Dufrene, Sahar Shekoohi, Christopher L Robinson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Suzetrigine, a NaMolecules (Basel, Switzerland) · 2026
    Review
  2. Cultural tailoring of pain management approaches: a scoping review.International journal for equity in health · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alan D KayeDepartment of Anesthesiology, Department of Pharmacology, Toxicology, and Neurosciences, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Driskell R GreeneSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Catherine NguyenSchool of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, 70112, LA, USA.
Amanda RaglandSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Mason P GrangerSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
William Peyton WilhiteSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Kylie DufreneSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71103, USA. sahar.shekoohi@lsuhs.edu.
Christopher L RobinsonBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe present investigation evaluated integration of novel medication technology to enhance treatment options, while improving patient outcomes in acute pain management. In this regard, we focused on determining the role of development and utilization of cutting-edge pharmaceutical advancements, such as targeted drug delivery systems, as well as non-pharmacologic interventions in addressing acute pain states. Further research in this area is warranted related to the need for increased patient comfort and reduced adverse effects. RECENT

findingsRecent innovations and techniques are discussed including pharmacologic drugs targeting sodium and calcium channels, peptide-based pharmacologic drugs, and non-medicinal methods of alleviating pain such as soothing music or virtual reality. The present investigation included review of current literature on the application of these innovative technologies, analyzing mechanisms of action, pharmacokinetics, and clinical effectiveness. Our study also investigated the potential benefits in terms of pain relief, reduced side effects, and improved patient adherence. The research critically examines the challenges and considerations associated with implementing these technologies in acute pain management, considering factors like cost, accessibility, and regulatory aspects. Additionally, case studies and clinical trials are highlighted which demonstrate practical implications of these novel medication technologies in real-world scenarios. The findings aim to provide healthcare professionals with a comprehensive understanding of the evolving landscape in acute pain management while guiding future research and clinical practices toward optimizing their use in enhancing patient care.

Indexed as

Acute PainCalcium Channel BlockersPain ManagementAnalgesicsHumansPeptidesSodium Channel BlockersAnalgesicsCalcium Channel BlockersPeptidesSodium Channel BlockersAcute pain managementCalcium channelCav2.2N-100NavsNovel medicationOpioidsSodium channelVX-548

Identifiers

PMID38761297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.