ArticleJournal of the American Heart Association2024
Mortality Benefits of Cardiac Rehabilitation in Coronary Artery Disease Are Mediated by Comprehensive Risk Factor Modification: A Retrospective Cohort Study.
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Cardiac Rehabilitation-Current Paradigms and Challenges Across the Cardiovascular Continuum.Journal of clinical medicine · 2026Review
- World Heart Federation Roadmap on cardiac rehabilitation: a pathway to lifelong cardiovascular health.Nature reviews. Cardiology · 2026Review
- Social Inequality in the Comprehensive Cardiac Rehabilitation Pathway: A Nationwide Cohort Study Across Hospitals and Primary Health Care Centers.Journal of cardiopulmonary rehabilitation and prevention · 2026Article
- The Effectiveness and Current Challenges of Home-Based Cardiac Telerehabilitation for Patients with Coronary Artery Disease: A Narrative Review.Journal of multidisciplinary healthcare · 2026Review
- Implementation and Strategies to Support Adoption of the World Heart Federation Roadmap on Cardiac Rehabilitation: A Pathway to Improve Lifelong Cardiovascular Health.Global heart · 2026Review
- Acute Coronary Syndromes: State-of-the-Art Diagnosis, Management, and Secondary Prevention.Journal of clinical medicine · 2025Review
- Impact of Body Composition on Peak Oxygen Uptake After Cardiac Rehabilitation.medRxiv : the preprint server for health sciences · 2025Article
- Cardiac Rehabilitation in the Modern Era: Evidence, Equity, and Evolving Delivery Models Across the Cardiovascular Spectrum.Journal of clinical medicine · 2025Review
- Knowledge, attitude, and practice of cardiac rehabilitation referral among healthcare professionals in China: A mediation model.Preventive medicine reports · 2025Article
- Women's Improvements in Cardiorespiratory Fitness Following Cardiac Rehabilitation Differ by Body Mass Index Category.CJC open · 2025Article
- Different Intensities of Exercise and Cardiovascular Performance: A Review : Different Intensities of Exercise and pCardiovascular Performance.Galen medical journal · 2025Review
- Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac rehabilitation (CR) is a multicomponent intervention to reduce adverse outcomes from coronary artery disease, but its mechanisms are not fully understood. The aims of this study were to examine the impact of CR on survival and cardiovascular risk factors, and to determine potential mediators between CR attendance and reduced mortality. METHODS AND
resultsA retrospective mediation analysis was conducted among 11 196 patients referred to a 12-week CR program following an acute coronary syndrome event between 2009 and 2019. A panel of cardiovascular risk factors was assessed at a CR intake visit and repeated on CR completion. All-cause and cardiovascular mortality were ascertained via health care administrative data sets at mean 4.2-year follow-up (SD, 2.81 years). CR completion was associated with reduced all-cause (adjusted hazard ratio [HR], 0.67 [95% CI, 0.54-0.83]) and cardiovascular (adjusted HR, 0.57 [95% CI, 0.40-0.81]) mortality, as well as improved cardiorespiratory fitness, lipid profile, body composition, psychological distress, and smoking rates (
conclusionsCardiorespiratory fitness and lipid control partly explain the mortality benefits of CR and represent important secondary prevention targets.
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Registered trials
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