ArticleBMC gastroenterology2024
The association between dietary vitamin B1 intake and constipation: a population-based study.
Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Constipation in Older Adults: Pathophysiology, Clinical Impact, and Management Strategies.Geriatrics (Basel, Switzerland) · 2026Review
- Dietary Patterns and Incident Chronic Constipation in Three Prospective Cohorts of Middle- and Older-Aged Adults.Gastroenterology · 2025Article
- S-shaped association between hs-CRP/HDL-C index and overweight/obesity in children and adolescents: a population-based study.European journal of medical research · 2025Article
- Association of constipation with all-cause mortality among individuals with type 2 diabetes: A retrospective cohort study.Journal of diabetes investigation · 2025Article
- Association between dietary oxidative balance score and constipation: evidence from National Health and Nutrition Examination Survey.Frontiers in nutrition · 2025Article
- Thiamine, gastrointestinal beriberi and acetylcholine signaling.Frontiers in nutrition · 2025Review
- Association between dietary vitamin B2 intake and constipation: a nationwide cross-sectional study.Frontiers in medicine · 2025Article
- Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005-2020.Frontiers in nutrition · 2025Article
- Functional constipation in Chinese infants: disruptions in gut microbiota and urinary metabolome revealed by a cross-sectional analysis.Frontiers in microbiology · 2025Article
- Constipation and Cardiovascular Mortality Risk in Patients With Hypertension: A Long-Term Cohort Study.International journal of hypertension · 2025Article
- Therapeutic Mechanism of Zhuyang Tongbian Decoction in Treating Functional Constipation: Insights from a Pilot Study Utilizing 16S rRNA Sequencing, Metagenomics, and Metabolomics.International journal of general medicine · 2025Article
- Association between the composite dietary antioxidant index and constipation: Evidence from NHANES 2005-2010.PloS one · 2024Article
- The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005-2010.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous researches have indicated a correlation between the intake of dietary micronutrients and the occurrence of constipation. Nevertheless, the correlation between constipation and vitamin B1 remains uninvestigated. The main aim of this research was to examine the association between chronic constipation and the consumption of vitamin B1 in the diet among adult participants of the National Health and Nutrition Examination Survey (NHANES).
methodsThis study used data from the NHANES, a survey on health and nutrition conducted between 2005 and 2010. The respondents' dietary information was gathered by utilizing the 24-hour dietary records. Various statistical analyses, such as multiple logistic regression, subgroup analysis, and curve-fitting analysis, were employed to investigate the correlation between dietary intake of vitamin B1 and chronic constipation.
resultsIn the trial, there were 10,371 participants, out of which 1,123 individuals (10.8%) were identified as having chronic constipation. Fully adjusted multiple logistic regression analyses showed that increasing dietary intake of vitamin B1 (OR = 0.87, 95% CI: 0.77-0.99) was significantly associated with a reduced risk of constipation. Following adjustment for multiple variables in Model 3, the odds ratio (OR) and 95% confidence interval (CI) for the third tertile, in comparison to the first tertile (reference group), was 0.80 (0.65, 0.99). In addition, subgroup analyses and interaction tests showed a significant inverse association between vitamin B1 intake and the prevalence of constipation, especially among men, non-hypertensive, and non-diabetic individuals (all P-values less than 0.05).
conclusionThis research uncovered an inverse correlation between the consumption of vitamin B1 in the diet and the occurrence of chronic constipation. One potential explanation for this phenomenon is that the consumption of vitamin B1 in one's diet is linked to the softening of stools and an augmented occurrence of colonic peristalsis. Additional extensive prospective research is required to thoroughly examine the significance of thiamine in long-term constipation.
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