Evidence map›Paper›PMID 38760629›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Cognitive complaints in patients with untreated obstructive sleep apnea versus patients with neurological and respiratory diseases: prevalence, severity and risk factors.

Tim Vaessen, Ruth E Mark, Wouter De Baene, Karin Gehring, Sebastiaan Overeem, Margriet M Sitskoorn

Abstract readComparative Study
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tim VaessenDepartment of Psychiatry and Medical Psychology, Spaarne Gasthuis, Boerhaavelaan 22, 2035 RC, Haarlem, the Netherlands. tvaessen@spaarnegasthuis.nl.ORCID 0000-0003-0354-3935
Ruth E MarkDepartment of Cognitive Neuropsychology, Tilburg University, Tilburg, the Netherlands.
Wouter De BaeneDepartment of Cognitive Neuropsychology, Tilburg University, Tilburg, the Netherlands.
Karin GehringDepartment of Cognitive Neuropsychology, Tilburg University, Tilburg, the Netherlands.
Sebastiaan OvereemSleep Medicine Center "Kempenhaeghe", Heeze, the Netherlands.
Margriet M SitskoornDepartment of Cognitive Neuropsychology, Tilburg University, Tilburg, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLittle is known about cognitive complaints (self-reported problems in cognitive functioning) in patients with Obstructive Sleep Apnea (OSA). We compared the prevalence and severity of cognitive complaints in patients with untreated OSA to patients with neurological and respiratory diseases. We also studied risk factors for cognitive complaints across these diseases, including OSA.

methodsWe used a convenience sample to compare untreated OSA patients (N = 86) to patients with stroke (N = 166), primary brain tumor (N = 197) and chronic obstructive pulmonary disease (COPD, N = 204) on cognitive complaints (Cognitive Failure Questionnaire, CFQ), anxiety and depression (Hospital Anxiety and Depression Scale, HADS) and cognitive impairments using neuropsychological tests. We combined all patient groups (OSA, stroke, brain tumor and COPD) and studied potential risk factors (demographic variables, anxiety, depression and cognitive impairments) for cognitive complaints across all patient groups using regression analysis.

resultsThe prevalence of cognitive complaints was higher in OSA patients and complaints of forgetfulness and distractibility were more severe compared to stroke and primary brain tumor patients, but similar to or lower than COPD patients. Regression analysis for the combined sample of all patient groups showed that cognitive complaints were most strongly associated with symptoms of anxiety and depression.

conclusionA high rate of OSA reported clinically significant cognitive complaints, comparable to other respiratory and neurological patients. Symptoms of anxiety and depression are important risk factors for cognitive complaints in patients with various neurological and respiratory diseases. Future studies should examine the relation between anxiety, depression and cognitive complaints in patients with OSA.

Indexed as

Pulmonary Disease, Chronic ObstructiveSleep Apnea, ObstructiveStrokeAdultAgedAnxiety DisordersBrain NeoplasmsCognitive DysfunctionComorbidityCross-Sectional StudiesDepressive DisorderFemaleHumansMaleMiddle AgedNeuropsychological TestsBrain tumorCognitive complaintsCognitive functioningCognitive impairmentsObstructive sleep apneaPulmonary diseasesStroke

Identifiers

PMID38760629
PMCPMC11303468

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.