Evidence map›Paper›PMID 38760510›Full record

ArticleJournal of molecular neuroscience : MN2024

Exploring the Biological Overlapping Between Brain Calcifications and Tumorgenesis.

Enrico Souza de Godoy, João Ricardo Mendes de Oliveira

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Enrico Souza de GodoyMedical Science Center, Federal University of Pernambuco (UFPE), Av. da Engenharia, 531-611, Cidade Universitária, Recife, 50670-901, Pernambuco, Brazil. enrico.godoy@ufpe.br.ORCID http://orcid.org/0000-0001-8926-4886
João Ricardo Mendes de OliveiraMedical Science Center, Federal University of Pernambuco (UFPE), Av. da Engenharia, 531-611, Cidade Universitária, Recife, 50670-901, Pernambuco, Brazil.ORCID http://orcid.org/0000-0001-7474-9266

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 311664/2020-2
6 · The paper itself

Abstract

This article discusses a rare case of coexistent meningiomas and Primary familial brain calcification (PFBC). PFBC is a neurodegenerative disease characterized by brain calcifications and a variety of neuropsychiatric symptoms and signs, with pathogenic variants in specific genes. The study explores the potential link between PFBC and meningiomas, highlighting shared features like intralesional calcifications and common genes such as MEA6. The article also revisits PFBC patients developing other brain tumors, particularly gliomas, emphasizing the intersection of oncogenes like PDGFB and PDGFRB in both calcifications and tumor progression. In recent investigations, attention has extended beyond brain tumors to breast cancer metastasis, unveiling a noteworthy connection. These findings suggest a broader connection between brain calcifications and tumors, encouraging a reevaluation of therapeutic approaches for PFBC.

Indexed as

Brain NeoplasmsCalcinosisMeningiomaBrain DiseasesFemaleHumansMeningeal NeoplasmsBrain calcificationBrain TumorsMeningiomaNeurogeneticsTumorgenesis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.