Evidence map›Paper›PMID 38760480›Full record

ArticleLeukemia2024

The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category.

Michaela Kotrova, Eva Fronkova, Michael Svaton, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert and 9 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Michaela KotrovaDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0001-5394-1072
Eva FronkovaCLIP-Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0002-6900-8145
Michael SvatonCLIP-Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0003-2966-3687
Daniela DrandiHematology Division, Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
Felix SchönDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.
Patricia HoogeveenDepartment of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Jeremy HancockBristol Genetics Laboratory, Southmead Hospital, Bristol, UK.
Aneta SkotnicovaCLIP-Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
Anke SchilhabelDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.
Cornelia EckertDepartment of Pediatric Hematology and Oncology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Emmanuelle ClappierHematology Laboratory, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Gianni CazzanigaTettamanti Cente, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.ORCID 0000-0003-2955-4528
Beat W SchäferDepartment of Hematology, University Hospital, Zürich, Switzerland.ORCID 0000-0001-5988-2915
Jacques J M van DongenDepartment of Immunology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.ORCID 0000-0002-3650-7087
Matthias RitgenDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.
Christiane PottDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0009-0005-9260-8340
Vincent H J van der VeldenDepartment of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID 0000-0001-9457-3763
Jan TrkaCLIP-Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0002-9527-8608
Monika BrüggemannDepartment of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany. m.brueggemann@med2.uni-kiel.de.ORCID 0000-0001-5514-5010

Funding

Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) TRANSCAN/BMBF 179, the NOVEL ConsortiumGrantová Agentura, Univerzita Karlova (Charles University Grant Agency) GA UK 318321Ministerstvo Zdravotnictví Ceské Republiky (Ministry of Health of the Czech Republic) NU20-03-00284
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neoplasm, ResidualHumansReal-Time Polymerase Chain Reaction

Identifiers

PMID38760480
PMCPMC11216996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.