Evidence map›Paper›PMID 38760435›Full record

ArticleScientific reports2024

Mortality outcomes in diabetic metabolic dysfunction-associated fatty liver disease: non-obese versus obese individuals.

Pengwei Zhang, Yijun Zeng, Sijia Yang, Chunhong Ye, Mingwei Wang, Tianfang Peng, Li Li, Xianhui Dong

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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  3. Observational
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pengwei Zhang *Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China.
Yijun Zeng *Hangzhou Normal University, Hangzhou, 310015, China.
Sijia YangHangzhou Normal University, Hangzhou, 310015, China.
Chunhong YeHangzhou Normal University, Hangzhou, 310015, China.
Mingwei WangAffiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China.
Tianfang PengAffiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China.
Li LiHangzhou Normal University, Hangzhou, 310015, China. lislucy@163.com.
Xianhui DongAffiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China. tcmdongxianhui@126.com.

Funding

"Pioneer" and "Leading Goose" R&D Program of Zhejiang 2022C03138
6 · The paper itself

Abstract

The difference in the survival of obese patients and normal-weight/lean patients with diabetic MAFLD remains unclear. Therefore, we aimed to describe the long-term survival of individuals with diabetic MAFLD and overweight/obesity (OT2M), diabetic MAFLD with lean/normal weight (LT2M), MAFLD with overweight/obesity and without T2DM (OM), and MAFLD with lean/normal weight and without T2DM (LM). Using the NHANESIII database, participants with MAFLD were divided into four groups. Hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause, cardiovascular disease (CVD)-related, and cancer-related mortalities for different MAFLD subtypes were evaluated using Cox proportional hazards models. Of the 3539 participants, 1618 participants (42.61%) died during a mean follow-up period of 274.41 ± 2.35 months. LT2M and OT2M had higher risks of all-cause mortality (adjusted HR, 2.14; 95% CI 1.82-2.51; p < 0.0001; adjusted HR, 2.24; 95% CI 1.32-3.81; p = 0.003) and CVD-related mortality (adjusted HR, 3.25; 95% CI 1.72-6.14; p < 0.0001; adjusted HR, 3.36; 95% CI 2.52-4.47; p < 0.0001) than did OM. All-cause and CVD mortality rates in LT2M and OT2M patients were higher than those in OM patients. Patients with concurrent T2DM and MAFLD should be screened, regardless of the presence of obesity.

Indexed as

Diabetes Mellitus, Type 2ObesityAdultAgedCardiovascular DiseasesFemaleHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseProportional Hazards ModelsRisk FactorsMetabolic (dysfunction)-associated fatty liver diseaseMortalityNormal weightObesityType 2 diabetes mellitus

Identifiers

PMID38760435
PMCPMC11101429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.