Evidence map›Paper›PMID 38760054›Full record

Observational studyBMJ open2024

Cohort profile of an early life observational cohort in China: Bone and MicroBiOme onset (BAMBOO) study.

Jing Wang, Chang Jiang, Shuo Wang, Lingyan Feng, Yu Zhang, Yuanyuan Guo, Gongshu Liu, Xi Li, Guohong Zhang, Xiaowei Zhu and 11 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Gut microbiome in early life and bone health outcomes at age 6: a Danish mother-child cohort study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jing WangTianjin Women's and Children's Health Center, Tianjin, China.
Chang JiangTianjin Women's and Children's Health Center, Tianjin, China.
Shuo WangTianjin Women's and Children's Health Center, Tianjin, China.
Lingyan FengTianjin Women's and Children's Health Center, Tianjin, China.
Yu ZhangTianjin Women's and Children's Health Center, Tianjin, China.
Yuanyuan GuoTianjin Women's and Children's Health Center, Tianjin, China.
Gongshu LiuTianjin Women's and Children's Health Center, Tianjin, China.
Xi LiBGI Research, Wuhan, China.
Guohong ZhangBGI Research, Shenzhen, China.
Xiaowei ZhuBGI Research, Shenzhen, China.
Fangyi RenBGI Research, Shenzhen, China.
Lingyao GuanBGI Research, Shenzhen, China.
Jiayu ChenBGI Research, Shenzhen, China.
Ya GaoBGI Research, Shenzhen, China.
Mo ChenNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Noura DarwishClinical Research Unit, Nestlé Research, Lausanne, Switzerland.
Sara Colombo MottazClinical Research Unit, Nestlé Research, Lausanne, Switzerland.
Marie Noelle HorcajadaNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Nicolas BonnetNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Shaillay Kumar DograNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Dantong WangNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland dantong.wang@rdls.nestle.com.ORCID 0000-0003-2379-8222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Bone And MicroBiOme Onset (BAMBOO) study is an ongoing prospective observational cohort study conducted in Tianjin, China, aiming to determine age-appropriate trajectories for microbiome maturation and bone development and to identify the influence of dietary factors in the process.

participantsThe recruitment started in September 2021 and was completed in February 2023. A total of 1380 subjects were recruited, 690 at birth (group 1) and 690 at 6 months of age (group 2). Groups 1 and 2 will be followed up for 12 months and 36 months, respectively. FINDINGS TO DATE: The age of the mothers was 31.1±3.7 (mean±SD), and the birth weight of infants was 3.3±0.5 kg with an incidence of caesarean section 50.4%. Food diary information of the first 100 subjects showed that 64 food items were introduced by 6 months. A pilot microbiome analysis revealed that at the species level, bacterial communities were composed of mostly FUTURE PLANS: Data collection will be completed in August 2025. Four stage-statistical analyses will be performed as the cohort reaches certain age thresholds before the final report. Analysis of BAMBOO data will be used to develop age-appropriate trajectories for microbiome maturation and bone development for children aged 0-3 years and investigate the contribution of dietary factors in the process. TRIAL REGISTRATION NUMBER: ChiCTR2100049972.

Indexed as

Bone DevelopmentAdultChild, PreschoolChinaCohort StudiesDietFemaleGastrointestinal MicrobiomeHumansInfantInfant, NewbornMaleMilk, HumanProspective StudiesVitamin DVitamin Dbone healthearly life growthearly life nutritionMicrobiome

Identifiers

PMID38760054
PMCPMC11103194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.