Evidence map›Paper›PMID 38759904›Full record

Trial reportJournal of the American College of Cardiology2024

Impact of Anatomical and Viability-Guided Completeness of Revascularization on Clinical Outcomes in Ischemic Cardiomyopathy.

Saad M Ezad, Margaret McEntegart, Matthew Dodd, Matthaios Didagelos, Novalia Sidik, Matthew Li Kam Wa, Holly P Morgan, Antonis Pavlidis, Roshan Weerackody, Simon J Walsh and 9 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of the American College of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01920048 (REVascularisation for Ischaemic VEntricular Dysfunction), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01920048 nacompletednot on this map

REVascularisation for Ischaemic VEntricular Dysfunction (REVIVED): a Randomized Comparison of Percutaneous Coronary Intervention (With Optimal Medical Therapy) Versus Optimal Medical Therapy Alone for Treatment of Heart Failure Secondary to Coronary Disease

TypeinterventionalSponsorKing's College LondonRan2013 to 2022Enrolled700ConditionsIschemic CardiomyopathyArmsPercutaneous Coronary Intervention, Drug Therapy for Heart Failure, Device Therapy for Heart Failure
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Guideline for Chronic Coronary Syndrome - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Saad M EzadBritish Heart Foundation Centre of Research Excellence at the School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, United Kingdom.
Margaret McEntegartWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, United Kingdom; Columbia University Medical Center, New York, New York, USA.
Matthew DoddClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Matthaios DidagelosWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, United Kingdom.
Novalia SidikWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, United Kingdom.
Matthew Li Kam WaBritish Heart Foundation Centre of Research Excellence at the School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, United Kingdom.
Holly P MorganBritish Heart Foundation Centre of Research Excellence at the School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, United Kingdom.
Antonis PavlidisGuy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Roshan WeerackodyBarts Health NHS Trust, London, United Kingdom.
Simon J WalshBelfast Health and Social Care NHS Trust, Belfast, United Kingdom.
James C SprattSt George's Hospital, University of London, London, United Kingdom.
Julian StrangeUniversity Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.
Peter LudmanInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom.
Amedeo ChiribiriGuy's and St Thomas' NHS Foundation Trust, London, United Kingdom; Department of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Tim ClaytonClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Mark C PetrieSchool of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.
Peter O'KaneUniversity Hospitals Dorset NHS Foundation Trust, Bournemouth, United Kingdom.
Divaka PereraBritish Heart Foundation Centre of Research Excellence at the School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, United Kingdom; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom. Electronic address: divaka.perera@kcl.ac.uk.
REVIVED-BCIS2 Investigators

Funding

British Heart Foundation FS/CRTF/21/24118
6 · The paper itself

Abstract

backgroundComplete revascularization of coronary artery disease has been linked to improved outcomes in patients with preserved left ventricular (LV) function.

objectivesThis study sought to identify the impact of complete revascularization in patients with severe LV dysfunction.

methodsPatients enrolled in the REVIVED-BCIS2 (Revascularization for Ischemic Ventricular Dysfunction) trial were eligible if baseline/procedural angiograms and viability studies were available for analysis by independent core laboratories. Anatomical and viability-guided completeness of revascularization were measured by the coronary and myocardial revascularization indices (RI

resultsOf 700 randomized patients, 670 were included. The baseline BCIS-JS and SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) scores were 8 (Q1-Q3: 6-10) and 22 (Q1-Q3: 15-29), respectively. In those patients assigned to PCI, median RI

conclusionsIn patients with severe LV dysfunction, neither complete anatomical nor viability-guided revascularization was associated with improved event-free survival compared with incomplete revascularization or treatment with medical therapy alone. (Revascularization for Ischemic Ventricular Dysfunction) [REVIVED-BCIS2]; NCT01920048).

Indexed as

Myocardial IschemiaMyocardial RevascularizationAgedCardiomyopathiesCoronary AngiographyFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionTreatment OutcomeVentricular Dysfunction, Leftcomplete revascularizationheart failureleft ventricular dysfunctionpercutaneous coronary interventionstable coronary artery disease

Identifiers

PMID38759904
PMCPMC11250908

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.