ArticleEnvironmental research2024
Determinants of per- and polyfluoroalkyl substances (PFAS) exposure among Wisconsin residents.
Article in Environmental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Associations between perfluoroalkyl substances and multiple sclerosis in U.S. cohorts compared with NMOSD, MOGAD, and healthy controls.Environmental research · 2026Article
- Biomonitoring of per- and polyfluoroalkyl substances (PFAS) in sportfish consumers in the Great Lakes - Milwaukee, Wisconsin.Journal of exposure science & environmental epidemiology · 2026Article
- Occupational predictors of serum per- and polyfluoroalkyl substance concentrations in a national biomonitoring survey of adults in Canada.Journal of exposure science & environmental epidemiology · 2026Article
- Associations of serum PFAS with COVID-19 antibody levels among fully vaccinated adults.Environmental research · 2026Article
- Metabolomics of per- and polyfluoroalkyl substances (PFAS) exposure: Advances in LC-MS technology and applications.Journal of food and drug analysis · 2026Review
- Urine-to-Blood Partitioning of Per- and Polyfluoroalkyl Substances in Human Biomonitoring: Implications for Environmental Exposure Analysis and Bioaccumulation Assessment.Molecules (Basel, Switzerland) · 2026Review
- Per- and Polyfluoroalkyl Substances and Hand Osteoarthritis: Data From the Osteoarthritis Initiative.Arthritis & rheumatology (Hoboken, N.J.) · 2026Article
- Efficacy and Threat Language in PFAS Messaging.Risk analysis : an official publication of the Society for Risk Analysis · 2026Article
- Associations Between Seafood Consumption and Serum PFAS Levels Among Asian/Pacific Islanders in the San Francisco Bay Area, California.Exposure and health · 2026Article
- The moderating role of vitamin E in the association between PFAS exposures and diabetes risk: Evidence from the NHANES 2017-2018.Metabolism open · 2025Article
- Exploring the Association Between Per- and Polyfluoroalkyl Substances Exposure and the Risk of Stroke: A Systematic Investigation Using NHANES Data Analysis, Network Toxicology and Molecular Docking Approaches.Brain and behavior · 2025Article
- Does Home and Wild Food Procurement Enhance Food Security in High-Income Countries?Current environmental health reports · 2025Review
- Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling.Reproductive toxicology (Elmsford, N.Y.) · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundPer- and polyfluoroalkyl substances (PFAS) include thousands of manufactured compounds with growing public health concerns due to their potential for widespread human exposure and adverse health outcomes. While PFAS contamination remains a significant concern, especially from ingestion of contaminated food and water, determinants of the variability in PFAS exposure among regional and statewide populations in the United States remains unclear.
objectivesThe objective of this study was to leverage The Survey of the Health of Wisconsin (SHOW), the only statewide representative cohort in the US, to assess and characterize the variability of PFAS exposure in a general population.
methodsThis study sample included a sub-sample of 605 adult participants from the 2014-2016 tri-annual statewide representative sample. Geometric means for PFOS, PFOA, PFNA, PFHxS, PFPeS, PFHpA, and a summed measure of 38 analyzed serum PFAS were presented by demographic, diet, behavioral, and residential characteristics. Multivariate linear regression was used to determine significant predictors of serum PFAS after adjustment.
resultsOverall, higher serum concentrations of long-chain PFAS were observed compared with short-chain PFAS. Older adults, males, and non-Hispanic White individuals had higher serum PFAS compared to younger adults, females, and non-White individuals. Eating caught fish in the past year was associated with elevated levels of several PFAS. DISCUSSION: This is among the first studies to characterize serum PFAS among a representative statewide sample in Wisconsin. Both short- and long-chain serum PFAS were detectable for six prominent PFAS. Age and consumption of great lakes fish were the most significant predictors of serum PFAS. State-level PFAS biomonitoring is important for identifying high risk populations and informing state public health standards and interventions, especially among those not living near known contamination sites.
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