Evidence map›Paper›PMID 38759121›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2024

Long-Term Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Noninferiority Study Comparing Two Fractionation Schedules in Patients With Low-Risk Prostate Cancer.

W Robert Lee, James J Dignam, Mahul B Amin, Deborah W Bruner, Daniel Low, Gregory P Swanson, Amit B Shah, David D'Souza, Jeff M Michalski, Ian S Dayes and 8 more

Abstract readClinical Trial, Phase IIIRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Early Outcomes of Stereotactic Body Radiotherapy for Localized Prostate Cancer: A Retrospective Analysis.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2026
    Article
  12. Article
  13. Article
  14. Management of high-risk prostate cancer in Spain: results from a national patterns of care survey.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. How to tailor the radiotherapy after radical prostatectomy in the modern era of molecular imaging, genomic testing, and technology development?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

W Robert LeeDuke University Medical Center, Durham, NC.ORCID 0000-0002-3545-0170
James J DignamDepartment of Public Health Sciences, University of Chicago, Chicago, IL.
Mahul B AminCedars-Sinai Medical Center, Los Angeles, CA.
Deborah W BrunerEmory University, Atlanta, GA.ORCID 0000-0002-5770-9948
Daniel LowUniversity of California, Los Angeles, Los Angeles, CA.
Gregory P SwansonBaylor Scott & White Healthcare Temple Clinic, Temple, TX.ORCID 0000-0002-7959-1493
Amit B ShahYork Cancer Center, York, PA.
David D'SouzaLondon Regional Cancer Program, London, ON, Canada.
Jeff M MichalskiWashington University School of Medicine, St Louis, MO.ORCID 0000-0003-0563-3766
Ian S DayesMcMaster University, Hamilton, ON, Canada.ORCID 0000-0001-8550-1485
Samantha A SeawardKaiser Permanente Northern California, Santa Clara, CA.ORCID 0000-0003-4459-4923
William A HallMedical College of Wisconsin, Milwaukee, WI.ORCID 0000-0001-7017-6755
Paul L NguyenDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Thomas M PisanskyMayo Clinic, Rochester, MN.
Sergio L FariaMcGill University Health Center, Montreal, QC, Canada.
Yuhchyau ChenUniversity of Rochester Medical Center, Wilmot Cancer Institute, Rochester, NY.
Joseph P RodgersNRG Oncology Statistics and Data Management Center, Philadelphia, PA.
Howard M SandlerCedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-8193-5769

Funding

NRG Oncology Network Group Operations Center - GY9 BIQSFP Reports/BudgetsU10CA180868 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI NORMAN WOLMARK · 2014 to 2026
$206.8M
RTOG Foreign AccrualU10CA021661 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI CURRAN, WALTER J. · 1985 to 2013
$150.3M
Statistics CoreU10CA180822 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mei-Yin C Polley · 2014 to 2026
$146.4M
NRG Oncology NCORP Research Base-BIQSFPUG1CA189867 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Deborah Watkins Bruner, Lisa A. Kachnic · 2014 to 2026
$140.5M
RTOG Foreign AccrualsU10CA037422 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI BRUNER, DEBORAH WATKINS · 1985 to 2013
$30.4M
ADVANCED TECHNOLOGY QA CENTERU24CA081647 · NCI · WASHINGTON UNIVERSITY · PI MICHALSKI, JEFF M. · 1999 to 2013
$22.8M
NCI NIH HHS U10 CA021661NCI NIH HHS U10 CA037422NCI NIH HHS U10 CA180822NCI NIH HHS U10 CA180868NCI NIH HHS U24 CA081647NCI NIH HHS UG1 CA189867
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dose Fractionation, RadiationProstatic NeoplasmsAgedDisease-Free SurvivalHumansMaleMiddle AgedRadiation Dose Hypofractionation

Identifiers

PMID38759121
PMCPMC11377096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.