Evidence map›Paper›PMID 38758473›Full record

ArticleCurrent microbiology2024

Isolation of a CTX-M-55 (ESBL)-Producing Escherichia coli Strain of the Global ST6448 Clone from a Captive Orangutan in the USA.

Carly M Smith, Melissa Anacker, Durward L Bevis, Nicole A M Dutton, Dan Powell, Richard William McLaughlin

Abstract read
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Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. ESBL-ProducingVeterinary sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carly M SmithSchool of Liberal Arts and Sciences, Gateway Technical College, Kenosha, WI, 53144, USA.
Melissa AnackerMinnesota Department of Health, Public Health Laboratory - Infectious Disease Laboratory, St. Paul, MN, 55155, USA.
Durward L BevisSchool of Liberal Arts and Sciences, Gateway Technical College, Kenosha, WI, 53144, USA.
Nicole A M DuttonSchool of Liberal Arts and Sciences, Gateway Technical College, Kenosha, WI, 53144, USA.
Dan PowellRacine Zoo, 2131 North Main Street Racine, Racine, WI, 53402, USA.
Richard William McLaughlinSchool of Liberal Arts and Sciences, Gateway Technical College, Kenosha, WI, 53144, USA. mclaughlinr@gtc.edu.ORCID http://orcid.org/0000-0003-4634-7096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine if orangutans (Pongo spp.) living in captivity at a zoo in Wisconsin were colonized with antimicrobial-resistant bacteria and, if found, to identify underlying genetic mechanisms contributing to their resistant phenotypes. We hypothesize that since antimicrobial-resistant bacteria are so prevalent within humans, the animals could also be carriers of such strains given the daily contact between the animals and the zoo staff that care for them. To test this theory, fecal samples from two orangutans were examined for resistant bacteria by inoculation on HardyCHROM™ ESBL and HardyCHROM™ CRE agars. Isolates were identified using MALDI-TOF mass spectrometry and antimicrobial susceptibility testing was performed using a Microscan autoSCAN-4 System. An isolate was selected for additional characterization, including whole genome sequencing (WGS). Using the Type (Strain) Genome Server (TYGS) the bacterium was identified as Escherichia coli. The sequence type identified was (ST/phylogenetic group/β-lactamase): ST6448/B1/CTX-M-55.

Indexed as

beta-LactamasesEscherichia coliEscherichia coli InfectionsFecesAnimalsAnimals, ZooAnti-Bacterial AgentsEscherichia coli ProteinsGenome, BacterialMicrobial Sensitivity TestsPhylogenyWhole Genome SequencingWisconsinAnti-Bacterial Agentsbeta-LactamasesEscherichia coli Proteins

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.