Evidence map›Paper›PMID 38758324›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Measuring Urease and Phospholipase Secretion in Cryptococcus neoformans.

Hunter J Hoffman, Erin E McClelland

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hunter J HoffmanDepartment of Biomedical Sciences, Marian University College of Osteopathic Medicine, Indianapolis, IN, USA.
Erin E McClellandDepartment of Biomedical Sciences, Marian University College of Osteopathic Medicine, Indianapolis, IN, USA. emcclelland@marian.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urease and phospholipase are enzymes that are important virulence factors for Cryptococcus neoformans. These are two of the most studied enzymes involved in how C. neoformans breaches the blood-brain barrier. Additionally, phospholipase secretion also supports dissemination from the lungs. This chapter describes the methods used to measure the secretion of these enzymes, which may be used to characterize strain invasiveness and virulence.

Indexed as

Cryptococcus neoformansPhospholipasesUreaseCryptococcosisFungal ProteinsHumansVirulenceVirulence FactorsFungal ProteinsPhospholipasesUreaseVirulence FactorsCryptococcusPhospholipaseUreaseVirulence

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.