Evidence map›Paper›PMID 38758217›Full record

SynthesisClinical and experimental medicine2024

Epidemiology of malignant tumors in patients with pemphigus: an analysis of trends from 1955 to 2021.

Yue Luo, Xiaoya Fei, Mingxia Wang, Han Yang, Ying Zhang, Yiran Chen, Ying Luo, Xiaojie Ding, Chunjie Gao, Fang Shen and 6 more

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yue Luo *Shanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Xiaoya FeiShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Mingxia WangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Han YangDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Ying ZhangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Yiran ChenDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Ying LuoInstitute of Dermatology, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 201203, China.
Xiaojie DingDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Chunjie GaoShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Fang ShenShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Ruiping WangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Bin LiShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China.
Le KuaiDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Qi ZhengShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China. drzheng0@163.com.
Miao LiDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. 864604088@qq.com.
Jiankun SongShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, 200443, China. 1607247615@qq.com.

Funding

Chen Guang project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation 22CGA50Clinical Incubation Program lcfy2022-10Health Young Talents of Shanghai Municipal Health Commission 2022YQ026Shanghai Clinical Key Specialty Construction Project shslczdzk05001Shanghai Dermatology Hospital demonstration research ward project SHDC2023CRW009Shanghai Dermatology Research Center 2023ZZ02017Shanghai Municipal Health Commission Health Industry Clinical Research Special Project 20234Y0269The Shanghai Development Office of TCM ZY(2021-2023)-0209-13Xinglin Youth Scholar of Shanghai University of Traditional Chinese Medicine RY411.33.10Youth Talent Promotion Project of China Association of Traditional Chinese Medicine (2021-2023) Category A CACM-2021-QNRC2-A10
6 · The paper itself

Abstract

backgroundThe incidence of malignant tumors has increased in patients with non-paraneoplastic pemphigus, although there has been no systematic analysis of global epidemiology.

objectiveTo explore the epidemiology of various types of non-paraneoplastic pemphigus associated with malignant tumors.

methodsFive databases from establishment through October 20, 2023, were searched. STATA SE 17 was used for the data analysis. Subgroup, meta-regression, and sensitivity analyses were used to evaluate the heterogeneity of pooled studies.

resultsA total of 6679 participants were included in our meta-analysis from 16 studies. The aggregated prevalence of tumors in patients diagnosed with pemphigus was 8%. The prevalence was 7% in patients with pemphigus vulgaris, 10% in those with pemphigus foliaceus, and 12% in individuals diagnosed with other types of pemphigus. The prevalence was 8% in Asia, 11% in Europe, and 8% in North America. From a country-specific perspective, patients with pemphigus from Israel, Greece, and Germany exhibited a higher prevalence of tumors at 11%. Furthermore, when categorized by the duration of the study period, the highest prevalence was observed in studies spanning 10 to 20 years, at 11%.

conclusionThese findings demonstrate the incidence and prevalence of malignant tumors in patients with non-paraneoplastic pemphigus, which may achieve early detection and intervention, and then reduce mortality rates.

Indexed as

NeoplasmsPemphigusAsiaEuropeHumansIncidenceNorth AmericaPrevalenceEpidemiologyMalignant tumorsPemphigus

Identifiers

PMID38758217
PMCPMC11101525

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.