Evidence map›Paper›PMID 38757249›Full record

ArticlePhysiological reports2024

Exogenous erythropoietin increases hematological status, fat oxidation, and aerobic performance in males following prolonged strenuous training.

Devin J Drummer, Julie L McNiff, Emily E Howard, Jess A Gwin, Christopher T Carrigan, Nancy E Murphy, Marques A Wilson, Julia Michalak, Benjamin J Ryan, James P McClung and 2 more

Abstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Devin J DrummerMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Julie L McNiffMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Emily E HowardMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Jess A GwinMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Christopher T CarriganMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Nancy E MurphyMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Marques A WilsonMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Julia MichalakMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Benjamin J RyanThermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
James P McClungMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Stefan M PasiakosOffice of Dietary Supplements, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland, USA.
Lee M MargolisMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.ORCID 0000-0002-0652-1304

Funding

Military Operational Medicine Research ProgramUS Department of Energy DOE contract number DE-SC0014664US Medical Research and Development Command
6 · The paper itself

Abstract

This study investigated the effects of EPO on hemoglobin (Hgb) and hematocrit (Hct), time trial (TT) performance, substrate oxidation, and skeletal muscle phenotype throughout 28 days of strenuous exercise. Eight males completed this longitudinal controlled exercise and feeding study using EPO (50 IU/kg body mass) 3×/week for 28 days. Hgb, Hct, and TT performance were assessed PRE and on Days 7, 14, 21, and 27 of EPO. Rested/fasted muscle obtained PRE and POST EPO were analyzed for gene expression, protein signaling, fiber type, and capillarization. Substrate oxidation and glucose turnover were assessed during 90-min of treadmill load carriage (LC; 30% body mass; 55 ± 5% V̇O

Indexed as

ErythropoietinExerciseMuscle, SkeletalOxidation-ReductionAdultEnergy MetabolismHematocritHemoglobinsHumansLipid MetabolismMaleYoung AdultErythropoietinHemoglobinshematocrithemoglobinmitochondriasubstrate oxidationV̇O2peak

Identifiers

PMID38757249
PMCPMC11099744

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.