ReviewFrontiers in immunology2024
The aging lung: microenvironment, mechanisms, and diseases.
Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Effect of anesthetic nasal mask on hypoxemia in elderly patients undergoing gastroscopy with deep sedation: a randomized controlled trial.BMC gastroenterology · 2025Trial
- Perioperative care in older adults: a narrative review.European geriatric medicine · 2026Review
- Associations between vitamin B6 and vitamin B12 intake and lung function: A cross-sectional study based on NHANES 2007 to 2012.Medicine · 2026Article
- Safety of flexible bronchoscopy in elderly patients.BMC pulmonary medicine · 2026Article
- Gut microbiota-derived metabolites as immune modulators in aging and age-related chronic inflammatory diseases.Ageing research reviews · 2026Review
- CCL25/CCR9-induced M2 macrophage polarization promotes lung cancer progression via TGF-β1-mediated activation of the JAK/STAT-PIM2 signaling pathway.Molecular and cellular biochemistry · 2026Article
- Helper T cells and chemokines in elderly asthma - Mechanisms of airway inflammation and remodeling: A review.Biomolecules & biomedicine · 2026Review
- Trend Analysis of Respiratory Disease Mortality in the Population Aged 65 and over in Poland: Results from a Registry Study (2000-2022).Advances in respiratory medicine · 2026Article
- Senescent fibroblasts in aging and pulmonary fibrosis.Frontiers in aging · 2026Review
- Inflammatory biomarkers and 30-day thoracic outcomes after surgical versus non-surgical management of spontaneous pneumothorax: a retrospective cohort study.Frontiers in medicine · 2026Article
- The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Immune-metabolic positive feedback model in COPD: cross-mechanisms and potential intervention strategies.Frontiers in cell and developmental biology · 2026Review
- The association of frailty and mechanical power with hospital mortality in critically ill patients: a retrospective study based on the MIMIC-IV and eICU database.European journal of medical research · 2025Article
- Clinical characteristics and BGA-optimized pretest probability of pulmonary embolism in the elderly.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Article
- A Bayesian Informative Shrinkage Approach for Large-scale Multiple Hypothesis Testing (BISHOT): with Applications in Differential Analysis of Omics Data.bioRxiv : the preprint server for biology · 2025Article
- High seroprevalence and high risk: why are older adults more prone to respiratory syncytial virus?Journal of virology · 2025Review
- Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases.International journal of molecular sciences · 2025Review
- L-Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU-08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway.Aging cell · 2025Article
- The Aging Lung: Exploring Multimorbidity Patterns and Their Clinical Implications: A Narrative Review.Current issues in molecular biology · 2025Review
- Global Burden of Tracheal, Bronchus, and Lung Cancer in Adults Over 55 Years Old Based on Socio demographic Status and Geographical and Gender Differences from 2010-2021.Thoracic research and practice · 2025Article
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the development of global social economy and the deepening of the aging population, diseases related to aging have received increasing attention. The pathogenesis of many respiratory diseases remains unclear, and lung aging is an independent risk factor for respiratory diseases. The aging mechanism of the lung may be involved in the occurrence and development of respiratory diseases. Aging-induced immune, oxidative stress, inflammation, and telomere changes can directly induce and promote the occurrence and development of lung aging. Meanwhile, the occurrence of lung aging also further aggravates the immune stress and inflammatory response of respiratory diseases; the two mutually affect each other and promote the development of respiratory diseases. Explaining the mechanism and treatment direction of these respiratory diseases from the perspective of lung aging will be a new idea and research field. This review summarizes the changes in pulmonary microenvironment, metabolic mechanisms, and the progression of respiratory diseases associated with aging.
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