Evidence map›Paper›PMID 38756663›Full record

ArticleFrontiers in oncology2024

KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer.

Antonis Giannakakis, Margaritis Tsifintaris, Vasileios Gouzouasis, Ghim Siong Ow, Mei Yee Aau, Csaba Papp, Anna V Ivshina, Vladimir A Kuznetsov

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonis GiannakakisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Margaritis TsifintarisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Vasileios GouzouasisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Ghim Siong OwBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Mei Yee AauBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Csaba PappDepartment of Urology, The State University of New York (SUNY) Upstate Medical University, Syracuse, NY, United States.
Anna V IvshinaBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Vladimir A KuznetsovBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress-induced promoter-associated and antisense lncRNAs (si-paancRNAs) originate from a reservoir of oxidative stress (OS)-specific promoters via RNAPII pausing-mediated divergent antisense transcription. Several studies have shown that the KDM7A divergent transcript gene (

Indexed as

breast cancerDNA damage response and repairepithelial-to-mesenchymal transitiongenotoxic stressKDM7A-DTlncRNA alterationoxidative stressTP53 mutation

Identifiers

PMID38756663
PMCPMC11097164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.