Evidence map›Paper›PMID 38756124›Full record

ArticleJPGN reports2024

Cause or effect? Undetectable vitamin D in a patient with Crohn's disease.

Julia Esswein, Maggie Vickers, Michael Kleinman, John Whitworth, Mark Corkins, S Riley Pace

Abstract readCase Reports
In one paragraph

Article in JPGN reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia EssweinDivision of Internal Medicine and Pediatrics University of Tennessee Health Sciences Center Memphis Tennessee USA.
Maggie VickersDivision of Gastroenterology LeBonheur Children's Hospital Memphis Tennessee USA.
Michael KleinmanDivision of Internal Medicine and Pediatrics University of Tennessee Health Sciences Center Memphis Tennessee USA.
John WhitworthDivision of Gastroenterology LeBonheur Children's Hospital Memphis Tennessee USA.
Mark CorkinsDivision of Gastroenterology LeBonheur Children's Hospital Memphis Tennessee USA.
S Riley PaceDivision of Internal Medicine and Pediatrics University of Tennessee Health Sciences Center Memphis Tennessee USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease has been described as the "great mimicker" with a wide array of presentations. We describe a case of a teenager who presented with tetany and undetectable vitamin D as initial presentation of Crohn's disease. There are reports of adults in tetany due to electrolyte derangements in chronic gastrointestinal diseases secondary to malabsorption. However, the role of deficient vitamin D as it contributes to immune system dysfunction has only begun to be explored. Vitamin D is essential for calcium absorption, immune regulation, and gut epithelial barrier. This case report discusses vitamin D physiology and its potential mediation in the pathogenesis of inflammatory bowel disease.

Indexed as

calcium absoprtioncathelicidinimmune system regulationtoll‐like‐receptors

Identifiers

PMID38756124
PMCPMC11093929

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.