Evidence map›Paper›PMID 38756108›Full record

ArticleJPGN reports2024

Coronavirus HKU1 infection and development of pediatric acute liver failure with immune dysregulation phenotype.

Arun Ajmera, Peter Joseph Pernicone, Nishant Patel, Stefany Hernandez Benabe

Abstract readCase Reports
In one paragraph

Article in JPGN reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arun AjmeraCenter for Digestive Health and Nutrition Arnold Palmer Hospital for Children Orlando Florida USA.ORCID https://orcid.org/0009-0007-2640-8070
Peter Joseph PerniconeAdvent Health at Orlando Advent Health for Children Orlando Florida USA.
Nishant PatelCenter for Digestive Health and Nutrition Arnold Palmer Hospital for Children Orlando Florida USA.
Stefany Hernandez BenabeAdvent Health Medical Group Pediatric Gastroenterology at Orlando Advent Health for Children Orlando Florida USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric acute liver failure is a rare but serious complication of Coronavirus infections. Our patient is a previously healthy 8-year-old male who presented with acute liver failure in the setting of human coronavirus HKU1 (HCoV-HKU1) infection while asymptomatic from a respiratory perspective. During the hospital course, he developed acute hepatic encephalopathy and was listed for liver transplantation, but fortunately recovered remaining status 7 (inactive) on the transplant list. With a negative diagnostic evaluation other than his viral infection and hyperdense CD8 T-cells on liver immunohistochemical staining, pediatric acute liver failure (PALF) immune dysregulation phenotype was diagnosed.

Indexed as

abnormal liver enzymesacute hepatitiscoagulopathydirect hyperbilirubinemiahyperimmune liver disease

Identifiers

PMID38756108
PMCPMC11093931

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.