ArticleInvestigative ophthalmology & visual science2020
Relationship Between Acuity and Contrast Sensitivity: Differences Due to Eye Disease.
Article in Investigative ophthalmology & visual science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Contrast Sensitivity Impairment in Diabetic Retinopathy: Clinical and Structural Correlates.Diagnostics (Basel, Switzerland) · 2026Review
- Modalities of vision restoration in optic neuropathies and retinal disease.Progress in retinal and eye research · 2026Review
- Effect of membrane peeling on the ganglion cell inner-plexiform layer in glaucomatous eyes with idiopathic epiretinal membrane.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Prevalence of Hearing, Vision and Cognitive Impairment and Impact in Older Adults in Home Care: A Study Protocol.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Ohio Contrast Cards are reliable and robust to blur under cycloplegia in visually normal children.Optometry and vision science : official publication of the American Academy of Optometry · 2025Article
- Retinal and Choroidal Morphological Features Influencing Contrast Sensitivity in Retinitis Pigmentosa.Medicina (Kaunas, Lithuania) · 2025Article
- Elevated Visual Crowding in CRB1-Associated Retinopathies: Understanding Functional Visual Deficits Using Child-Friendly Computerized Testing.Investigative ophthalmology & visual science · 2025Article
- Stratification of the Extent of Visual Impairment Identifies Sex-Specific Degenerative Changes in Retinal Structure and Function during Aging.Journal of integrative neuroscience · 2025Article
- Single and Multiple Visual Function Impairments and Associated- Vision-Related Quality of Life Impact in Older Adults Aged 60 to 100 Years.Investigative ophthalmology & visual science · 2025Article
- Exploring the impact of visual function degradation on manual prehension movements in normal-sighted individuals.PloS one · 2025Article
- Assessing Contrast Sensitivity Function in CRB1-Retinopathies: Exploring Child-Friendly Measures of Visual Function.Translational vision science & technology · 2024Article
- Quantifying the Functional Relationship Between Visual Acuity and Contrast Sensitivity Function.Investigative ophthalmology & visual science · 2024Article
- Update on Clinical Trial Endpoints in Gene Therapy Trials for Inherited Retinal Diseases.Journal of clinical medicine · 2024Review
- Estimating Visual Acuity Without a Visual Acuity Chart.Translational vision science & technology · 2024Article
- Impact of Glaucomatous Ganglion Cell Damage on Central Visual Function.Annual review of vision science · 2024Review
- Assessment of visual function in blind mice and monkeys with subretinally implanted nanowire arrays as artificial photoreceptors.Nature biomedical engineering · 2024Article
- Association of Contrast Sensitivity With Eye Disease and Vision-Related Quality of Life.American journal of ophthalmology · 2024Article
- Article
- Object recognition via echoes: quantifying the crossmodal transfer of three-dimensional shape information between echolocation, vision, and haptics.Frontiers in neuroscience · 2024Article
- The effect of femtosecond laser-assistedFrontiers in neuroscience · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Purpose: Visual acuity (VA) and contrast sensitivity (CS) characterize different aspects of visual function. Whereas VA is a standard test in routine eye exams and clinical trials, CS is often not included. We investigated the pathology-specific dissociation between VA and CS by quantifying and comparing the relationship between these two measures in common ocular pathologies. Methods: VA and CS data were assembled from 1113 subjects, including groups with cataract (n = 450), age-related macular degeneration (AMD; n = 232), glaucoma (n = 100), retinitis pigmentosa (RP; n = 87), and normal ocular health (n = 244). VA and CS were measured by the Early Treatment Diabetic Retinopathy Study chart and Pelli-Robson chart, respectively. Results: Even when VA was relatively normal (<0.3 logMAR), the four ocular pathology groups showed quantitatively different mean CS deficits relative to normal controls, ranging from -0.01 log units for cataract to 0.23 log units for RP. When the entire range of VA was considered, the corresponding deficits in CS were noticeably different across these four groups, being least for cataract and progressively more severe for glaucoma, AMD, and RP. For every 1.0 logMAR loss of VA, the corresponding deficit in CS ranged from 0.22 logCS for cataract to 0.97 logCS for RP. Conclusions: The quantitative relationship between VA and CS depends on the ocular pathology. CS appears to provide valuable complementary information to VA in the early detection of eye disease and when evaluating visual impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.