Evidence map›Paper›PMID 38755753›Full record

ArticleMolecular pharmaceutics2024

The Influence of PVP Polymer Topology on the Liquid Crystalline Order of Itraconazole in Binary Systems.

Luiza Orszulak, Taoufik Lamrani, Roksana Bernat, Magdalena Tarnacka, Daniel Żakowiecki, Karolina Jurkiewicz, Patryk Zioła, Anna Mrozek-Wilczkiewicz, Andrzej Zięba, Kamil Kamiński and 1 more

Abstract read
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In one paragraph

Article in Molecular pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luiza OrszulakInstitute of Chemistry, Faculty of Science and Technology, University of Silesia in Katowice, Szkolna 9, 40-007 Katowice, Poland.ORCID 0000-0002-7709-5867
Taoufik LamraniInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.
Roksana BernatDepartment of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellonska 4, 41-200 Sosnowiec, Poland.
Magdalena TarnackaInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.ORCID 0000-0002-9444-3114
Daniel ŻakowieckiChemische Fabrik Budenheim KG, Rheinstrasse 27, 55257 Budenheim, Germany.
Karolina JurkiewiczInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.ORCID 0000-0002-4289-7827
Patryk ZiołaInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.
Anna Mrozek-WilczkiewiczInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.
Andrzej ZiębaDepartment of Organic Chemistry, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Jagiellonska 4, 41-200 Sosnowiec, Poland.
Kamil KamińskiInstitute of Physics, Faculty of Science and Technology, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.ORCID 0000-0002-5871-0203
Ewa KamińskaDepartment of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellonska 4, 41-200 Sosnowiec, Poland.ORCID 0000-0001-9725-8654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a novel approach by utilizing poly(vinylpyrrolidone)s (PVPs) with various topologies as potential matrices for the liquid crystalline (LC) active pharmaceutical ingredient itraconazole (ITZ). We examined amorphous solid dispersions (ASDs) composed of ITZ and (

Indexed as

Calorimetry, Differential ScanningItraconazoleLiquid CrystalsPovidoneSolubilityX-Ray DiffractionAntifungal AgentsChemistry, PharmaceuticalCrystallizationDrug CompoundingPolymersAntifungal AgentsItraconazolePolymersPovidoneamorphous solid dispersionsbinary mixturesitraconazoleliquid crystalline ordernematic phasepoly(vinylpyrrolidone)smectic phasestar-shaped polymer

Identifiers

PMID38755753
PMCPMC11151211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.