Evidence map›Paper›PMID 38755725›Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Molecular mechanisms of ferroptosis and its effects on bladder cancer.

Ruijie Li, Yiping Ning, Yacheng Yuan, Xukai Yang

Abstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruijie LiFirst School of Clinical Medical, Gansu University of Chinese Medicince, Lanzhou 730000. 1786420780@qq.com.
Yiping NingFirst School of Clinical Medical, Gansu University of Chinese Medicince, Lanzhou 730000.
Yacheng YuanGansu Provincial Key Laboratory of Stem Cell and Gene Drug, Lanzhou 730050, China.
Xukai YangDepartment of Urology, 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou 730050. yangxk125@126.com.

Funding

the Talent Innovation and Entrepreneurship Program of Lanzhou 2021-RC-106
6 · The paper itself

Abstract

Bladder cancer (BC) is one of the 3 common malignant tumors in the urinary system, with high incidence, easy metastasis, poor therapeutic efficacy, and poor prognosis, which seriously threatens the health of human. Tumor cells exhibit a strong demand for iron, and iron overload can induce ferroptosis, which is an iron dependent cell death caused by lipid peroxidation and cell membrane damage. Therefore, ferroptosis has strong anti-tumor potential. The molecular mechanisms of ferroptosis is associated with abnormalities in cellular phospholipid metabolism and iron metabolism, and dysregulation of antioxidant and non-antioxidant systems Xc

Indexed as

FerroptosisIronLipid PeroxidationPhospholipid Hydroperoxide Glutathione PeroxidaseUrinary Bladder NeoplasmsAmino Acid Transport System y+AntioxidantsGlutathioneHumansPhospholipidsAmino Acid Transport System y+AntioxidantsGlutathioneIronPhospholipid Hydroperoxide Glutathione PeroxidasePhospholipidsbladder cancerferroptosisferroptosis relevant moleculesiron metabolismlipid peroxidationphospholipid metabolismXc-/glutathione/glutathione peroxidase 4

Identifiers

PMID38755725
PMCPMC11103069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.