Evidence map›Paper›PMID 38755478›Full record

ArticleJournal of racial and ethnic health disparities2025

Environmental Levels of Volatile Organic Compounds, Race, and Socioeconomic Markers Correlate with Areas of High Colorectal Cancer Incidence.

Allie Jin, Natalie DuPré, Rochelle Holm, Ted Smith, Sandy Kavalukas

Abstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Allie JinSchool of Medicine, Department of Surgery, University of Louisville, 550 South Jackson Street, Louisville, KY, 40292, USA.ORCID 0000-0002-9130-7424
Natalie DuPréSchool of Public Health and Information Sciences, Department of Epidemiology and Population Health, University of Louisville, Louisville, KY, USA.
Rochelle HolmSchool of Medicine, Envirome Institute, University of Louisville, Louisville, KY, USA.
Ted SmithSchool of Medicine, Envirome Institute, University of Louisville, Louisville, KY, USA.
Sandy KavalukasSchool of Medicine, Department of Surgery, University of Louisville, 550 South Jackson Street, Louisville, KY, 40292, USA. sandy.kavalukas@louisville.edu.

Funding

University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
NIEHS NIH HHS P30 ES030283
6 · The paper itself

Abstract

backgroundAmbient levels of volatile organic compounds (VOCs) released from nearby industrial plants have shown positive associations with increased colorectal cancer (CRC) rates. The objective of this study is to analyze the distribution of CRC in the context of socioeconomic status and its correlation with community environmental data.

methodsA retrospective study analyzed CRC patients from 2021 to 2023. The census tracts of the patients' residential addresses were obtained, and CRC rates were calculated for each census tract. Socioeconomic data was gathered on these communities. Environmental VOC measurements were obtained from the National Scale Air Toxics Assessment. All datapoints were compared to statewide levels.

resultsThree census tracts in the county had higher CRC cases comparatively. These areas exhibited higher incidence rates and localized clusters of CRC cases, higher distribution of Black or African Americans, lower household incomes, lower home values, and lower educational attainment. VOC measurements in these census tracts had higher levels compared to county and state averages: specifically, 10.68% higher than county and 48.07% higher than state benzene levels (0.52 µg/m

conclusionThis study illustrates a positive correlation between higher ambient exposure to VOCs with increased CRC incidence. These findings underscore the potential interplay of environmental factors, socioeconomic determinants, and environmental injustice when considering strategies to address health disparities and CRC incidence.

Indexed as

Air PollutantsColorectal NeoplasmsEnvironmental ExposureVolatile Organic CompoundsAgedBlack or African AmericanFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesSocial ClassSocioeconomic FactorsUnited StatesWhiteAir PollutantsVolatile Organic CompoundsColorectal cancerEnvironmentSocioeconomic disparitiesVolatile organic compounds

Identifiers

PMID38755478
PMCPMC12981245

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.