Evidence map›Paper›PMID 38755406›Full record

ArticleScientific reports2024

Aspartic protease supplementation enhancing the performance, carcass characteristics, nutrient digestibility and economic viability, without changing blood parameters and salivary cortisol of pigs.

Thiago Augusto da Cruz, Bruno Bracco Donatelli Muro, Eduardo Machado Costa Lima, Valéria Dos Santos Moreira, Julio Cesar Carrera de Carvalho, Cesar Augusto Pospissil Garbossa, Leandro Batista Costa

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thiago Augusto da CruzGraduate Program in Animal Science, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, St. Imaculada Conceição, 1155, Curitiba, PR, 80215-901, Brazil.
Bruno Bracco Donatelli MuroSchool of Veterinary Medicine and Animal Science, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, SP, 13635-900, Brazil.
Eduardo Machado Costa LimaMcassab Indústria e Comércio, Av. das Nações Unidas, 20.882, São Paulo, SP, 04795-000, Brazil.
Valéria Dos Santos MoreiraMcassab Indústria e Comércio, Av. das Nações Unidas, 20.882, São Paulo, SP, 04795-000, Brazil.
Julio Cesar Carrera de CarvalhoMcassab Indústria e Comércio, Av. das Nações Unidas, 20.882, São Paulo, SP, 04795-000, Brazil.
Cesar Augusto Pospissil GarbossaSchool of Veterinary Medicine and Animal Science, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, SP, 13635-900, Brazil.
Leandro Batista CostaGraduate Program in Animal Science, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, St. Imaculada Conceição, 1155, Curitiba, PR, 80215-901, Brazil. batista.leandro@pucpr.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aiming to study the performance, carcass characteristics, nutrient digestibility, blood parameters, salivary cortisol levels, and economic viability of pigs administered aspartic protease, a total of 135 pigs were housed in pens in a randomized block design, divided into five treatments with nine replications. The experimental diets were positive control (PC), basic diet with a 5.0% reduction in protein and amino acid requirements; negative control (NC) with a 7.5% reduction in protein and amino acid requirements; NC + 100 g/mT of aspartic protease (NC100); NC + 150 g/mT of aspartic protease (NC150); and NC + 200 g/mT of neutral serine protease (NC200). The inclusion of protease, independently of the source and amount, increased the average daily weight gain (P < 0.05) of animals compared with the control treatments (PC and NC), improved feed conversion (P < 0.05) in early stages, and improved diet digestibility (P < 0.05) compared with the PC. Treatment with NC150 and NC200 resulted in greater carcass weights (P < 0.05) than treatment with the PC. NC100 led to a greater carcass yield than PC (P < 0.05), and NC150 resulted in a greater loin eye area than PC (P < 0.05). No differences (P > 0.05) in the blood parameters or salivary cortisol levels were found. Regarding economic viability, proteases increased the profitability, with NC150 leading to the best results. Thus, the use of aspartic proteases is recommended to improve performance and further facilitate pork production.

Indexed as

Animal FeedAspartic Acid ProteasesDietary SupplementsDigestionHydrocortisoneSalivaAnimal Nutritional Physiological PhenomenaAnimalsDietMaleSwineAspartic Acid ProteasesHydrocortisoneAnimal welfareEnzymesHematological analyzesProteinSwine

Identifiers

PMID38755406
PMCPMC11099141

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.