Evidence map›Paper›PMID 38755124›Full record

ArticleNature communications2024

E-cardiac patch to sense and repair infarcted myocardium.

Renjie Qiu, Xingying Zhang, Chen Song, Kaige Xu, Huijia Nong, Yi Li, Xianglong Xing, Kibret Mequanint, Qian Liu, Quan Yuan and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Review
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  9. Review
  10. Article
  11. Article
  12. Soft robotic devices for cardiovascular medicine.Nature reviews. Cardiology · 2026
    Review
  13. Review
  14. Review
  15. Review
  16. Materials Advances in Devices for Heart Disease Interventions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  17. Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  18. Review
  19. Article
  20. Advances in 2D materials for wearable biomonitoring.Materials science & engineering. R, Reports : a review journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Renjie Qiu *Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering; Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China.
Xingying Zhang *Department of Mechanical Engineering, University of Manitoba, Winnipeg, MB, Canada.
Chen Song *The Fifth Affiliated Hospital of Southern Medical University, Southern Medical University, Guangdong, Guangzhou, China.
Kaige XuDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, MB, Canada.
Huijia NongGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering; Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China.
Yi LiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences; Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, Guangzhou, Guangdong Province, China.ORCID http://orcid.org/0000-0001-8643-4501
Xianglong XingGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering; Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China.
Kibret MequanintDepartment of Chemical and Biochemical Engineering, and School of Biomedical Engineering, The University of Western Ontario, London, ON, Canada.ORCID http://orcid.org/0000-0002-7888-418X
Qian LiuDepartment of Applied Computer Science, University of Winnipeg, Winnipeg, MB, Canada.
Quan YuanState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0002-2836-1081
Xiaomin SunSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Malcolm XingDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, MB, Canada. malcolm.xing@umanitoba.ca.ORCID http://orcid.org/0000-0002-3547-0462
Leyu WangGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering; Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, China. wangleyu889@163.com.ORCID http://orcid.org/0000-0002-6547-1490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conductive cardiac patches can rebuild the electroactive microenvironment for the infarcted myocardium but their repair effects benefit by carried seed cells or drugs. The key to success is the effective integration of electrical stimulation with the microenvironment created by conductive cardiac patches. Besides, due to the concerns in a high re-admission ratio of heart patients, a remote medicine device will underpin the successful repair. Herein, we report a miniature self-powered biomimetic trinity triboelectric nanogenerator with a unique double-spacer structure that unifies energy harvesting, therapeutics, and diagnosis in one cardiac patch. Trinity triboelectric nanogenerator conductive cardiac patches improve the electroactivity of the infarcted heart and can also wirelessly monitor electrocardiosignal to a mobile device for diagnosis. RNA sequencing analysis from rat hearts reveals that this trinity cardiac patches mainly regulates cardiac muscle contraction-, energy metabolism-, and vascular regulation-related mRNA expressions in vivo. The research is spawning a device that truly integrates an electrical stimulation of a functional heart patch and self-powered e-care remote diagnostic sensor.

Indexed as

Myocardial InfarctionAnimalsElectric StimulationHumansMaleMyocardial ContractionMyocardiumRatsRats, Sprague-Dawley

Identifiers

PMID38755124
PMCPMC11099052

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.