Evidence map›Paper›PMID 38754886›Full record

ArticleBMJ open2024

Research priorities for the management of major trauma: an international priority setting partnership with the James Lind Alliance.

Christopher Patrick Bretherton, Robert Hirst, Hamez Gacaferi, Jonathan Gower, Lauren Exell, Scott Johnston, Shan Martin, Caroline Leech, Catherine Hilton, Ceri Battle and 15 more

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Consensus-based research priorities for post-collision care in the Western Cape province of South Africa.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Christopher Patrick BrethertonBone and Joint Health, Queen Mary University of London Faculty of Medicine and Dentistry, London, UK c.bretherton@qmul.ac.uk.ORCID 0000-0001-9569-0734
Robert HirstDepartment of Emergency, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Hamez GacaferiDepartment of General Surgery, Haaglanden Medisch Centrum Bronovo, Den Haag, The Netherlands.
Jonathan GowerJames Lind Alliance, Southampton, UK.
Lauren ExellBone and Joint Health, Queen Mary University of London Faculty of Medicine and Dentistry, London, UK.
Scott JohnstonPatient Representative, Yorkshire, UK.
Shan MartinPatient Representative, Wessex, UK.
Caroline LeechEmergency Department, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.ORCID 0000-0002-5301-9798
Catherine HiltonBone and Joint Health, Queen Mary University of London Faculty of Medicine and Dentistry, London, UK.
Ceri BattleWelsh Institute of Biomedical and Emergency Medicine Research, Swansea Bay University Health Board, Port Talbot, UK.ORCID 0000-0002-7503-1931
Daniel AxelrodTrauma and Orthopaedics, McMaster University, Hamilton, Ontario, Canada.
Heather VallierCase Western Reserve University Hospital, Cleveland, Ohio, USA.
Daphne Van EmbdenDepartment of Trauma Surgery, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
David J StocktonDepartment of Orthopaedics, The University of British Columbia Faculty of Medicine, Vancouver, British Columbia, Canada.
Elaine ColeTrauma Sciences, Queen Mary University of London, London, UK.
Julia WilliamsCollege of Paramedics, Bridgwater, UK.
Louise JohnsonClinical Psychology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Maritz LaubscherOrthopaedic Trauma Service, Division of Orthopaedic Surgery, University of Cape Town Faculty of Health Sciences, Capetown, South Africa.
Melissa WebbAlfred Hospital, Melbourne, Victoria, Australia.
Philip BraudeCLARITY (Collaborative Ageing Research), North Bristol NHS Trust, Tetbury, UK.
Sarah NorrisOccupational Therapy, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Steve BellMedical Directorate, North West Ambulance Service NHS Trust, Bolton, UK.ORCID 0000-0003-3891-6623
Sithombo MaqungoOrthopaedic Trauma Service, Division of Orthopaedic Surgery, University of Cape Town Faculty of Health Sciences, Observatory, South Africa.
Xavier Luke GriffinBone and Joint Health, Barts and The London School of Medicine and Dentistry, London, UK.ORCID 0000-0003-2976-7523
Major Trauma Priority Setting Partnership Steering Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study is to determine research priorities for the management of major trauma, representing the shared priorities of patients, their families, carers and healthcare professionals. DESIGN/

settingAn international research priority-setting partnership.

participantsPeople who have experienced major trauma, their carers and relatives, and healthcare professionals involved in treating patients after major trauma. The scope included chest, abdominal and pelvic injuries as well as major bleeding, multiple injuries and those that threaten life or limb.

methodsA multiphase priority-setting exercise was conducted in partnership with the James Lind Alliance over 24 months (November 2021-October 2023). An international survey asked respondents to submit their research uncertainties which were then combined into several indicative questions. The existing evidence was searched to ensure that the questions had not already been sufficiently answered. A second international survey asked respondents to prioritise the research questions. A final shortlist of 19 questions was taken to a stakeholder workshop, where consensus was reached on the top 10 priorities.

resultsA total of 1572 uncertainties, submitted by 417 respondents (including 132 patients and carers), were received during the initial survey. These were refined into 53 unique indicative questions, of which all 53 were judged to be true uncertainties after reviewing the existing evidence. 373 people (including 115 patients and carers) responded to the interim prioritisation survey and 19 questions were taken to a final consensus workshop between patients, carers and healthcare professionals. At the final workshop, a consensus was reached for the ranking of the top 10 questions.

conclusionsThe top 10 research priorities for major trauma include patient-centred questions regarding pain relief and prehospital management, multidisciplinary working, novel technologies, rehabilitation and holistic support. These shared priorities will now be used to guide funders and teams wishing to research major trauma around the globe.

Indexed as

Health PrioritiesCaregiversFemaleHealth PersonnelHumansMaleMultiple TraumaResearchSurveys and QuestionnairesWounds and Injuriesaccident & emergency medicinemusculoskeletal disorderstrauma management

Identifiers

PMID38754886
PMCPMC11107451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.