Evidence map›Paper›PMID 38753748›Full record

ReviewCancer journal (Sudbury, Mass.)

Molecular Imaging of Steroid Receptors in Breast Cancer.

Quinton J Keigley, Amy M Fowler, Sophia R O'Brien, Farrokh Dehdashti

Abstract readReview
In one paragraph

Review in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quinton J KeigleyFrom the Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Sophia R O'BrienDepartment of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-2685-101
Farrokh DehdashtiDivision of Nuclear Medicine, Edward Mallinckrodt Institute of Radiology, Alvin J. Siteman Cancer Center, Washington University School of Medicine, St Louis, MO.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WASHINGTON UNIVERSITY CO-CLINICAL IMAGING RESEARCH RESOURCEU24CA209837 · NCI · WASHINGTON UNIVERSITY · PI Li Ding, Shunqiang Li · 2017 to 2026
$6.3M
FFNP-PET as a predictive biomarker of response to endocrine therapy approaches in advanced breast cancerR01CA273194 · NCI · WASHINGTON UNIVERSITY · PI DEHDASHTI, FARROKH, MA, CYNTHIA X · 2022 to 2025
$3.1M
Precision Imaging of Breast Cancer for Guiding Neoadjuvant Endocrine TherapyR01CA272571 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI FOWLER, AMY · 2022 to 2025
$3.0M
ASSESSMENT OF FUNCTIONAL STATUS OF ESTROGEN RECEPTORS IN BREAST CANCER BY PETR01CA195450 · NCI · WASHINGTON UNIVERSITY · PI DEHDASHTI, FARROKH · 2015 to 2017
$701k
NCI NIH HHS P30 CA014520NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA195450NCI NIH HHS R01 CA272571NCI NIH HHS R01 CA273194NCI NIH HHS U24 CA209837
6 · The paper itself

Abstract

abstractSteroid receptors regulate gene expression for many important physiologic functions and pathologic processes. Receptors for estrogen, progesterone, and androgen have been extensively studied in breast cancer, and their expression provides prognostic information as well as targets for therapy. Noninvasive imaging utilizing positron emission tomography and radiolabeled ligands targeting these receptors can provide valuable insight into predicting treatment efficacy, staging whole-body disease burden, and identifying heterogeneity in receptor expression across different metastatic sites. This review provides an overview of steroid receptor imaging with a focus on breast cancer and radioligands for estrogen, progesterone, and androgen receptors.

Indexed as

Breast NeoplasmsMolecular ImagingPositron-Emission TomographyFemaleHumansRadiopharmaceuticalsReceptors, AndrogenReceptors, EstrogenReceptors, ProgesteroneReceptors, SteroidRadiopharmaceuticalsReceptors, AndrogenReceptors, EstrogenReceptors, ProgesteroneReceptors, Steroid

Identifiers

PMID38753748
PMCPMC11101139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.