Evidence map›Paper›PMID 38753374›Full record

Trial reportPsychological assessment2024

Longitudinal invariance of the Patient Health Questionnaire-9 among patients receiving pharmacotherapy for major depressive disorder: A secondary analysis of clinical trial data.

Daniel J Reis, Adam R Kinney, Jeri E Forster, Kelly A Stearns-Yoder, Julie A Kittel, Amanda E Wood, David W Oslin, Lisa A Brenner, Joseph A Simonetti

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological assessment, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel J ReisVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.ORCID 0000-0001-7806-3819
Adam R KinneyVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.
Jeri E ForsterVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.
Kelly A Stearns-YoderVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.
Julie A KittelVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.
Amanda E WoodVA Puget Sound Health Care System.
David W OslinCorporal Michael J. Crescenz VA Medical Center.
Lisa A BrennerVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.
Joseph A SimonettiVA Rocky Mountain Mental Illness Research, Education, and Clinical Center for Veteran Suicide Prevention.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Capital Solution DesignHSRD VA IP1 HX002375National Institutes of Health; National Center for Advancing Translational SciencesNCATS NIH HHS UL1 TR000445Rocky Mountain Mental Illness Research, Education, and Clinical CenterUS Department of Veterans Affairs; Health Services Research and Development ServiceUS Department of Veterans Affairs; Office of Academic Affiliations
6 · The paper itself

Abstract

Comparing self-reported symptom scores across time requires longitudinal measurement invariance (LMI), a psychometric property that means the measure is functioning identically across all time points. Despite its prominence as a measure of depression symptom severity in both research and health care, LMI has yet to be firmly established for the Patient Health Questionnaire-9 depression module (PHQ-9), particularly over the course of antidepressant pharmacotherapy. Accordingly, the objective of this study was to assess for LMI of the PHQ-9 during pharmacotherapy for major depressive disorder. This was a secondary analysis of data collected during a randomized controlled trial. A total of 1,944 veterans began antidepressant monotherapy and completed the PHQ-9 six times over 24 weeks of treatment. LMI was assessed using a series of four confirmatory factor analysis models that included all six time points, with estimated parameters increasingly constrained across models to test for different aspects of invariance. Root-mean-square error of approximation of the chi-square difference test values below 0.06 indicated the presence of LMI. Exploratory LMI analyses were also performed for separate sex, age, and race subgroups. Root-mean-square error of approximation of the chi-square difference test showed minimal change in model fits during invariance testing (≤ 0.06 for all steps), supporting full LMI for the PHQ-9. LMI was also supported for all tested veteran subgroups. As such, PHQ-9 sum scores can be compared across extended pharmacotherapy treatment durations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Indexed as

Antidepressive AgentsMajor Depressive DisorderPatient Health QuestionnairePsychometricsAdultAgedFactor Analysis, StatisticalFemaleHumansLongitudinal StudiesMaleMiddle AgedVeteransAntidepressive Agents

Identifiers

PMID38753374
PMCPMC11915754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.