Evidence map›Paper›PMID 38753266›Full record

ReviewJournal of applied genetics2024

HOXA9 versus HOXB9; particular focus on their controversial role in tumor pathogenesis.

Ahmed Hjazi, Saade Abdalkareem Jasim, Aiman Mohammed Baqir Al-Dhalimy, Pooja Bansal, Harpreet Kaur, Maytham T Qasim, Israa Hussein Mohammed, Mahamedha Deorari, Mohammed Abed Jawad, Ahmed Hussein Zwamel

Abstract readReview
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In one paragraph

Review in Journal of applied genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmed HjaziDepartment of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, 11942, Al-Kharj, Saudi Arabia.
Saade Abdalkareem JasimMedical Laboratory Techniques Department, Al-Maarif University College, Anbar, Iraq. saade.a.j@uoa.edu.iq.ORCID http://orcid.org/0009-0007-8087-809X
Aiman Mohammed Baqir Al-DhalimyDepartment of Nursing, Altoosi University College, Najaf, Iraq.
Pooja BansalDepartment of Biotechnology and Genetics, Jain (Deemed-to-Be) University, Bengaluru, Karnataka, 560069, India.
Harpreet KaurSchool of Basic & Applied Sciences, Shobhit University, Gangoh, Uttar Pradesh, 247341, India.
Maytham T QasimCollege of Health and Medical Technology, Al-Ayen University, Thi-Qar, Nasiriyah, 64001, Iraq.
Israa Hussein MohammedCollege of Nursing, National University of Science and Technology, Dhi Qar, Nasiriyah, Iraq.
Mahamedha DeorariUttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, India.
Mohammed Abed JawadDepartment of Medical Laboratories Technology, Al-Nisour University College, Baghdad, Iraq.
Ahmed Hussein ZwamelMedical Laboratory Technique College, The Islamic University, Najaf, Iraq.

Funding

Deanship of Scientific Research, Prince Sattam bin Abdulaziz University PSAU/2024/R/1445
6 · The paper itself

Abstract

The Homeobox (HOX) gene family is essential to regulating cellular processes because it maintains the exact coordination required for tissue homeostasis, cellular differentiation, and embryonic development. The most distinctive feature of this class of genes is the presence of the highly conserved DNA region known as the homeobox, which is essential for controlling their regulatory activities. Important players in the intricate process of genetic regulation are the HOX genes. Many diseases, especially in the area of cancer, are linked to their aberrant functioning. Due to their distinctive functions in biomedical research-particularly in the complex process of tumor advancement-HOXA9 and HOXB9 have drawn particular attention. HOXA9 and HOXB9 are more significant than what is usually connected with HOX genes since they have roles in the intricate field of cancer and beyond embryonic processes. The framework for a focused study of the different effects of HOXA9 and HOXB9 in the context of tumor biology is established in this study.

Indexed as

Homeodomain ProteinsNeoplasmsAnimalsGene Expression Regulation, NeoplasticHumanshomeobox protein HOXA9Homeodomain ProteinsHOXB9 protein, humanCancerHOXA9HOXB9HOX family

Identifiers

PMID38753266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.