Evidence map›Paper›PMID 38753222›Full record

ArticleInflammopharmacology2024

Novel combination of Olesoxime/Resveratrol-encapsulated exosomes to improve cognitive function by targeting amyloid β-induced Alzheimer's disease: investigation on in vitro and in vivo model.

Zhuo Wang, Chao Gao, Lei Zhang, Rubo Sui

Abstract read
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Article in Inflammopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhuo WangSchool of Nursing, Jinzhou Medical University, Jinzhou, 121099, China.
Chao GaoSchool of Nursing, Jinzhou Medical University, Jinzhou, 121099, China.
Lei ZhangSchool of Nursing, Jinzhou Medical University, Jinzhou, 121099, China.
Rubo SuiDepartment of Neurology, The First Affiliated Hospital of Jinzhou Medical University, No2, Section5, Renmin Street, Jinzhou, 121099, China. suirb@jzmu.edu.cn.ORCID http://orcid.org/0009-0000-7606-6901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a fatal neurological illness that worsens with time. Preventing the aggregate formation of amyloid beta protein is a promising approach to treat Alzheimer's disease. This article describes an amiable procedure for the synthesis of Olesoxime-Resveratrol (OLX-RSV) encapsulated in exosomes. By suppressing Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesCognitionDisease Models, AnimalExosomesResveratrolAnimalsApoptosisBlood-Brain BarrierCell Line, TumorHumansMaleMicePeptide FragmentsReactive Oxygen SpeciesAmyloid beta-Peptidesamyloid beta-protein (1-42)Peptide FragmentsReactive Oxygen SpeciesResveratrolAlzheimers diseaseAmyloid betaHuman neuroblastoma cellsOlesoximeResveratrol

Identifiers

PMID38753222

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.