Evidence map›Paper›PMID 38753112›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Dalbavancin as suppressive therapy for implant-related infections: a case series with therapeutic drug monitoring and review of the literature.

Barthelemy Lafon-Desmurs, Benoit Gachet, Benjamin Hennart, Benjamin Valentin, Gabrielle Roosen, Maxime Degrendel, Caroline Loiez, Eric Beltrand, Piervito D'Elia, Henri Migaud and 2 more

Abstract readReviewMulticenter Study
PubMed Publisher
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. TDM-Guided Dalbavancin Treatment for ComplexAntibiotics (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Vascular Graft Infections Due toMicroorganisms · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Barthelemy Lafon-DesmursCentre Hospitalier Gustave Dron, Department of Infectious Diseases, Service Universitaire Des Maladies Infectieuses, 59210, Tourcoing, France. blafondesmurs@ch-tourcoing.fr.
Benoit GachetCentre Hospitalier Gustave Dron, Department of Infectious Diseases, Service Universitaire Des Maladies Infectieuses, 59210, Tourcoing, France.
Benjamin HennartLille University Hospital, Department of Pharmacology and Toxicology, Lille, France.
Benjamin ValentinLille University Hospital, Department of Pharmacology, Lille, France.
Gabrielle RoosenCentre Hospitalier Gustave Dron, Department of Microbiology, Tourcoing, France.
Maxime DegrendelCentre Hospitalier Gustave Dron, Department of Infectious Diseases, Service Universitaire Des Maladies Infectieuses, 59210, Tourcoing, France.
Caroline LoiezLille University Hospital, Department of Microbiology, Lille, France.
Eric BeltrandCentre Hospitalier Gustave Dron, Department of Orthopedic Surgery, Tourcoing, France.
Piervito D'EliaCentre Hospitalier Gustave Dron, Départment of Vascular Surgery, Tourcoing, France.
Henri MigaudLille University Hospital, Department of Orthopedic Surgery, Lille, France.
Olivier RobineauCentre Hospitalier Gustave Dron, Department of Infectious Diseases, Service Universitaire Des Maladies Infectieuses, 59210, Tourcoing, France.
Eric SennevilleCentre Hospitalier Gustave Dron, Department of Infectious Diseases, Service Universitaire Des Maladies Infectieuses, 59210, Tourcoing, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implant-related infections may need suppressive antibiotic therapy (SAT). We describe a SAT strategy using dalbavancin with therapeutic drug monitoring (TDM). This is a retrospective bicentric study of patients with implant-related infection who received dalbavancin SAT between January 2021 and September 2023. Fifteen patients were included. Median number of injections was 4 (IQR: 2-7). Median time between two reinjections was 57 days (IQR 28-82). Dalbavancin plasma concentrations were above 4 mg/L for 97.9% of dosages (93/95) and above 8 mg/L for 85% (81/95). These results support the use of dalbavancin SAT for implant-related infections.

Indexed as

Anti-Bacterial AgentsDrug MonitoringProsthesis-Related InfectionsTeicoplaninAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesAnti-Bacterial AgentsdalbavancinTeicoplaninDalbavancinDosageProsthetic joint infectionSuppressive therapyVascular graft infection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.