ReviewAngewandte Chemie (International ed. in English)2024
Redox Approaches to Carbene Generation in Catalytic Cyclopropanation Reactions.
Review in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Iron-Catalyzed Cyclopropanation of Allenes Using Unactivated Alkyl Sulfonium Salts.Angewandte Chemie (International ed. in English) · 2026Article
- Direct Access to Iron Carbenes from Aldehyde, Ketone, and Formamide Feedstocks.Journal of the American Chemical Society · 2026Article
- Divergent synthesis of γ-lactones and cyclopropanes via efficient [1 + 4] and [1 + 2] annulations of amide-sulfoxonium ylides.Communications chemistry · 2026Article
- Catalytic Methods for the Transfer of Nonstabilized Carbenes.ACS catalysis · 2026Review
- Ring Strain-Promoted Activation of Pyridines by a Saturated BSiAngewandte Chemie (International ed. in English) · 2026Article
- Catalytic Reductive Annulation Reactions of Alkenes Using Dihaloalkanes.Tetrahedron letters · 2025Article
- Metal-Catalyzed Fluoroacetyl Carbene Transfer from Sulfonium Salts.Organic letters · 2025Article
- Carbenoid Reactions Promoted by Solids: From Lewis to Brønsted Catalysts.Accounts of chemical research · 2025Article
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Authors and funding
2 authors.
Funding
Abstract
Transition metal-catalyzed carbene transfer reactions have a century-old history in organic chemistry and are a primary method for the synthesis of cyclopropanes. Much of the work in this field has focused on the use of diazo compounds and related precursors, which can transfer a carbene fragment to a catalyst with concomitant loss of a stable byproduct. Despite the utility of this approach, there are persistent limitations in the scope of viable carbenes, most notably those lacking stabilizing substituents. By coupling carbene transfer chemistry with two-electron redox cycles, it is possible to expand the available starting materials that can be used as carbene precursors. In this Minireview, we discuss emerging catalytic reductive cyclopropanation reactions using either gem-dihaloalkanes or carbonyl compounds. This strategy is inspired by classic stoichiometric transformations, such as the Simmons-Smith cyclopropanation and the Clemmensen reduction, but instead entails the formation of a catalytically generated transition metal carbene or carbenoid. We also present recent efforts to generate carbenes directly from methylene (CR
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.